In written testimony posted ahead of Congressional hearing tomorrow, Moderna president Stephen Hoge notes the company is in the process of 'onboarding' another fill-finish partner (along w Catalent) for its #covid19 vaccine in the US: https://docs.house.gov/meetings/IF/IF02/20210223/111226/HHRG-117-IF02-Wstate-HogeS-20210223.pdf …
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J&J updates on expected
#covid19 vaccine supply in written congressional testimony for hearing tomorrow: 20M+ doses to US by end of March, assuming necessary regulatory approvals re: manufacturing (100M total by end of June; 1-dose vaccine): https://docs.house.gov/meetings/IF/IF02/20210223/111226/HHRG-117-IF02-Wstate-NettlesR-20210223.PDF …Show this thread -
AZ notes in congressional testimony that recruitment for its US ph3
#covid19 vaccine trial is now complete. Bc infection rate has been high, "we are hopeful that the readout of the data will be available in the coming weeks." https://docs.house.gov/meetings/IF/IF02/20210223/111226/HHRG-117-IF02-Bio-DobberR-20210223.pdf …Show this thread -
AZ notes in testimony its US phase 3
#covid19 vaccine trial uses a 4-week interval for the doses, which "may not maximize efficacy" compared to a longer dosing schedule. (https://docs.house.gov/meetings/IF/IF02/20210223/111226/HHRG-117-IF02-Bio-DobberR-20210223.pdf …)Show this thread -
AZ says in testimony it's benefited from use of Defense Production Act: "Since the Defense Production Act Title I priority rating was put in place, our suppliers have not communicated any significant delays of materials or equipment." Doesn't specify dose # if/when granted EUA
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AZ says it could take 8-9 months to update its
#covid19 vaccine to new variants, which it's already working on for P1 (Brazil) and B.1.351 (South Africa): "it is likely the process from start to finished product would take 8 to 9 months to complete."Show this thread -
Novavax says in testimony it plans to begin clinical testing of new
#covid19 vaccine candidates against variants in the first half of this year. With ph3 trial fully enrolled today, says it plans to complete FDA submission in Q2; supply: 110M doses by Q3: https://docs.house.gov/meetings/IF/IF02/20210223/111226/HHRG-117-IF02-Wstate-TrizzinoJ-20210223.pdf …Show this thread
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meg, do you know of any aggregate data on % of people who are opting out? there were early reports that up to 30% of HCWs were opting out.
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Meg - really appreciate your ultra informative reporting on all things coronavirus!
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Good stuff!! Not bad for a liberal arts major

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It’s funny how everyone forgets that the majority of kids have a fever/feel like crap after one or more of the prescribed vaccinations in the 1st 5 years. Vaccines induce immune responses.
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