Matthew Hufford

@mbhufford

Zea aficionado, evolutionary genomicist in EEOB department at Iowa State, marathoner

Ames, Iowa
Vrijeme pridruživanja: lipanj 2013.

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  1. 18. sij

    I am a Maize-Meeting-Abstract-Editing Machine! Holy cow that was a lot today. Mahalo to my lab and collaborators for churning these out!

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  2. 16. sij

    Pretty amazing result from the Dawe Lab and we enjoyed collaborating...telomere to telomere with no gaps for two chromosomes and 7/10 functional centromeres traversed without gaps. We also now know the structure of the Ab10 haplotype.

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  3. 14. sij

    Ok, Kevin Fengler in the session has me convinced to make the switch to HiFi data for future assemblies. More accurate than corrected CLR data and read length has really improved!

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  4. 11. sij

    Maggie Woodhouse from describing the massive overhaul of the website and database with the recent publication of nearly 50 maize genomes (including ).

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  5. 10. sij
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    9. sij

    I'm giving my first ever scientific talk at on how to use the to test classical questions about heterosis. Come see it Tuesday 11:50AM in the Terrace Room of the Handlery Hotel!

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    9. sij

    Maize V5 and a lot more... Proud and excited to be part of this effort! Check out the NAM project sites: and

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    9. sij

    The data from this project is now available at MaizeGDB including 26 genome pages, ~1 million gene models, 134 BLAST targets, and JBrowse instances for each genome with over 1,000 tracks of data.

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  9. 9. sij

    This has been a monumental but really fun effort due to an excellent team. Thanks to folks at UGA and CSHL and our group at ISU (Maggie Woodhouse, , , , , , Sarah Pedersen, Michael Syring). Preprint soon!

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    18. pro 2019.

    Our pre-print "Maximizing prediction of orphan genes in assembled genomes" is out today! "Orphan genes" share no sequence homology to genes in closely related genomes.

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  11. 16. pro 2019.

    Our TE annotation manuscript is out today in Genome Biology. We’ve identified the best-performing methods and created a pipeline for comprehensive annotation. Congrats to who did the heavy lifting and thanks to collaborators.

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    15. pro 2019.

    Outstanding postdoc opportunity at UofMinn. 2 years of funding + $5k/year in research expenses. Applications due Feb 3, 2020!

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  13. 10. pro 2019.

    Such a pleasure to work with talented undergrads like at . Chase describes how his appreciation of the importance of agricultural biodiversity has grown through participation in the program. Check out his blog post!

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  14. 6. pro 2019.

    A piece of advice that gave me years ago that’s stuck with me: during talks the focus should be empathy for your audience, which ensures 1) targeting information at the right level and 2) calms nerves because it’s about their understanding, not your performance.

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  15. 4. pro 2019.

    Current Status (Sorry SysAdmins, we really are trying to be good! 😬)

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    3. pro 2019.

    Gene regulatory effects of a large chromosomal inversion in highland maize

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  17. 29. stu 2019.

    Long-read and scaffolding technology have matured and are more economical. Our study of their application in a large, complex genome can be a guide as they are applied more broadly. Exciting to look forward to the Biology enabled by 10’s and 100’s of de novo genomes per species.

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  18. 29. stu 2019.

    This study helped guide assembly of the 26 founder lines of the maize NAM, which will be released in the coming months, was led by my postdoc (co-advised with ) and is in collaboration with the groups of and .

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  19. 29. stu 2019.

    We downsampled a high-depth PacBio dataset from 20-75x coverage and to read length N50 from 11-21kb, assembled subsets, scaffolded with a Bionano optical map, and characterized how fully various genomic elements were captured with each assembly of this complex genome.

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  20. 29. stu 2019.

    The preprint is up for our long-read genome assembly benchmarking study for the tropical maize line NC358.

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