'For you' tab makes me feel a lot more fatigued from using Twitter.
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Matt Krisiloff
@mattkrisiloff
CEO (turning stem cells into human eggs)
Started (helping scientists build companies)
prev worked at Y Combinator
Matt Krisiloff’s Tweets
What are the coolest technologies being worked on today?
One would definitely be In-vitro gametogenesis: turning stem cells into human eggs.
CEO breaks it down for us. 🧬
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We are looking for a lab manager ! If you or anyone you know has experience wants to work on a great team and would be interested in our mission: making human eggs from stem cells plz hit me up or apply! jobs.ashbyhq.com/Conception/88d
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Talked with about making eggs from stem cells, the starting days of OpenAI, and helping scientists start companies
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The average SciFounder Fellowship application this cycle feels stronger than in previous cycles.
It's clear a lot of strong scientists are increasingly planning to start their own companies.
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The custom where startups pay the VC's legal bills for a round closing is so stupid!
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Interested in #startups? Tune in to this week's episode featuring sharing how scientists can successfully launch companies. whensciencespeaks.com/MattKrisiloff #scientists
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TODAY is the deadline to apply for SciFounder Fellowship!
Get $400k + mentorship to start a hard science company of your own.
Email hello@scifounders.com if need more time.
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Deadline for Fellowship application is tomorrow! They have been immensely helpful in our journey going from a very early startup to a seed stage company.
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The deadline to apply for SciFounders Fellowship is in 8 days! $400k + mentorship for technical founders
We try and chat with as many applicants as possible so even if you don't get it, its a great chance to get feedback
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The scientist that made unauthorized CRISPR babies in China, , is now on twitter!
He has a new Beijing lab, is again working on gene therapies, and is apparently allowed to tweet when Twitter is banned in China (including tweeting a bit about his time in prison).
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Interesting that He Jiankui is quietly diving back into gene editing research (and live tweeting it?) after the global outcry for his use of CRISPR to edit embryos four years ago
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Some thoughts on why progress in biology is so slow. Suppose we *actually* want to cure all diseases by 2100, what should we do? We need to be able to do experiments faster in human biology, and we need a better approach to knowledge and talent.
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Enter the Compound Thesis Database
An experiment with a few of our working theses that we've pulled from our internal database & made public.
It's rough, but we hope it allows founders, operators, & investors to better connect with us & help us learn.
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You should read this if you haven’t yet.
It’s so remarkable how many of the worlds most important technologies were developed by scientists running their own companies.
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Founder-led biotech is not a new phenomenon. Despite a lot of skepticism and pushback (technical) founders have built and led very successful, multi-billion dollar biotech companies before.
I wanted to share a few of my favorite founding stories.
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The deadline to apply for SciFounder Fellowship is in 22 days!
Get $400k + mentorship to start a scientific company.
The application takes less than an hour.
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Founder-led biotech is not a new phenomenon. Despite a lot of skepticism and pushback (technical) founders have built and led very successful, multi-billion dollar biotech companies before.
I wanted to share a few of my favorite founding stories.
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If you want to start a company and need help, feel free to reach out!
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Timing-wise, things are good right now.
Financial markets are down, and a lot of jobs are less secure than they've been / shares you might have in your company may be less valuable.
On the flip side, there are still lots of early-stage investors that need to make investments!
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Companies are also great places to meet co-founders -- you will be around people you have already worked with on a team.
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Industry scientists see first-hand the problems well-funded companies are dealing with in their R&D and commercialization pipelines.
They are in ideal positions to come up with new ideas to address problems.
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It's a good time for industry scientists to start startups.
Most startups seem to be started by academic scientists, but industry scientists should take the idea of starting a company more seriously.
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Twitter is about to go through another ‘founding’ period with a lot of new users and a lot of new features.
It will be possible to get a lot of followers very quickly.
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Deep tech investors often overlook medtech because of the perception that medical devices address only niche problems. What a missed opportunity! Medical devices can cure some of the biggest diseases—and have corresponding large value propositions!
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Valuable single product medical device companies:
Intuitive Surgical: $93 billion market cap
Dexcom: $44 billion
Insulet: $20 billion twitter.com/mattkrisiloff/…
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1/ There are too many unanswered questions about women’s reproductive health.
❓Why does menopause occur?
❓What causes endometriosis and can we cure it?
❓What’s the impact of oral contraceptives on mental health?
To help find answers is launching !
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Valuable single product medical device companies:
Intuitive Surgical: $93 billion market cap
Dexcom: $44 billion
Insulet: $20 billion
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Medical devices are still vastly underestimated in their startup potential.
That is still a 'secret' where investors can make a massive return.
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We're hiring for another Stem Cell Scientist at !
No previous germ-cell experience necessary, but prior iPSC differentiation work is great.
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Signed up to try Twitter Blue for a month.
Feel like we should give it a chance and see if it's actually a better experience!
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It's a good time for industry scientists to start startups.
But that timing might not hold up for long!
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Medical devices are still vastly underestimated in their startup potential.
That is still a 'secret' where investors can make a massive return.
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Getting a lot of great applications. So nice to see so many technical teams with exciting ideas.
Keep them coming!! Deadline is December 15th.
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What makes a good scientific advisor for a hard tech start-up?
A few thoughts on what to look out for, why setting a high bar is important, and some diagnostics you can run to make sure it's a strong fit long-term.
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Opening a new round of SciFounder Fellowship!
If you're a scientist looking to start a company, we'll give you $400,000 + mentorship on how to get started.
Deadline to apply is December 15th.
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#jobalert #hiring
At we’re looking for an expert in #epigenetics to work in the field of #reproduction and #stemcells!
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if Science is successful, I hope we one day offer an apprenticeship program capable of taking talented 18 year olds and giving them a world-class technical education while they make money doing productive things at the same time
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Having the right co-founder(s) can make a big difference but teaming up with the wrong ones can damage a company.
A few thoughts on why the right chemistry is important, what to prioritize, and strategies to make sure you are a good fit long term.
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Lots of attention (rightly) on projections that China’s population might fall by ⚠️ roughly half ⚠️ by end of this century, but not sure people appreciate quite how widespread this dynamic is.
More than a dozen countries (most of them in Europe) are set to shrink even faster 📉
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Founders doing fundraising should be extremely paranoid until money is wired.
You should constantly plot on how to keep the ball moving.
Many early founders treat bits of positive momentum too passively, and that can be the difference between a successful or failed raise.
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A lot of fun at our retreat in Napa this weekend!
We have a lot of role openings still which can be checked out at conception.bio -- come join one of the best scientific startup teams that exist.
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No more journal paywalls for federally funded research!!
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Science startups should usually set up their own labs from the start -- great post by
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As a bio start-up: Set up your own lab as soon as possible.
Many technical teams we talked to flirt with the idea of running their experiments through CROs. In most cases that’s the wrong approach.
alexschubert.xyz/set-up-your-ow
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