Iain Mathieson

@mathiesoniain

Population genetics, ancient DNA, statistics.

Philadelphia, PA
Vrijeme pridruživanja: travanj 2012.

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  1. proslijedio/la je Tweet
    25. stu 2019.

    Apply to the funded DPhil in Genomic Medicine and Statistics - its a fantastic program! 🧬✨Deadline 10th February, 2020 🧬✨

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  2. proslijedio/la je Tweet

    our paper on deep learning to detect selection with is finally out time to check out ImaGene

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  3. proslijedio/la je Tweet
    22. stu 2019.

    Super excited to see our paper out in where we study transmission dynamics of mtDNA mutations during germline and somatic development in 96 multigenerational pedigrees.

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  4. proslijedio/la je Tweet
    19. stu 2019.

    IMHO 4 published archaic mixture episodes with strong DNA evidence: ~2% Neandertal ancestry mostly outside Africa 50-60ky (Green 2010) ~3% Denisovan in Oceania (Reich 2010) Neandertal ancestor of Oase1 (Fu 2015) ~0.1% Denisovan in East Asia (Browning 2018)

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    12. stu 2019.
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  6. 6. stu 2019.

    Looks awesome. Added to the "must read carefully" queue!

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  7. 28. lis 2019.

    I shouldn't be, but I am genuinely surprised that this sort of thing is still getting published in Nature. It's like it fell through a timewarp from 20 years ago.

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  8. proslijedio/la je Tweet
    23. lis 2019.

    Happy to see this work with out. Overview below:

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  9. proslijedio/la je Tweet
    16. lis 2019.

    Hey , come chat with me about my work with on impact of recent pop structure and ways to correct for it in GWAS. Implications for large-scale GWAS, rare variants, and burden tests. Poster: 3027/w, 2:00-3:00p!

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  10. proslijedio/la je Tweet
    15. lis 2019.

    Sadly not making it to . However, I am looking to hire a postdoc! If you are interested in working on questions in human population genetics, especially the evolution of complex traits and diseases, drop me a line!

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  11. 14. lis 2019.

    Inside my office!!

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  12. proslijedio/la je Tweet
    13. lis 2019.

    Proto-Indo-European speakers did milk (*h₂mlǵ-enti) their cows (*gʷeh₃ues) and sheep (*h₃eueis) to make cheese (*tuHrom). And maybe they also milked their mares (*h₁eḱueh₂es) to make kumis (*suleh₂). But were they able to digest fresh milk?

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  13. 12. lis 2019.
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  14. proslijedio/la je Tweet
    25. ruj 2019.

    We are so excited to host from next week. Please join us for his talk titled "The genetic basis of depression" on Monday 9/30 at 12PM in BRB!

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  15. 23. ruj 2019.

    I agree with John. This result seems inconsistent with my understanding of our ability to predict consequences of functional variation (e.g. effect of novel LoF mutations in disease genes). May be that this particular application is a special case, but its an extraordinary claim.

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  16. 20. ruj 2019.

    Was there polygenic selection for height in Europe?

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  17. proslijedio/la je Tweet
    7. kol 2019.

    We present our new data resource: Atlas of Variant Age & Shared Ancestry Database

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  18. 1. kol 2019.

    For someone who calls themselves a population geneticist, I sure am bad at spelling the word "population".

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  19. 18. srp 2019.

    has a poster about the evolution of skin pigmentation in Europe, and I am presenting Sam Cox's work on the evolution of human height (preprint here: ). Come and say hi!

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  20. 18. srp 2019.

    Looking forward to SMBE. Several members & friends of the lab are involved: talking about Mt-Nuclear interactions at 11:00/M. reconstructing Amish founder genomes 4.30/Tue. winning the GBE Student paper prize (!) at the awards ceremony 5:00/Th

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