Mario Peña-Hernández  

@marioph13

2nd Year Virology Ph.D. Student at . 🇲🇽 . God is good.

New Haven, CT
Joined September 2016
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  1. Pinned Tweet
    Mar 25

    I am beyond THRILLED to announce that I will be working on my Ph.D. thesis under the mentorship of Dr. Akiko Iwasaki and Dr. Craig Wilen to study some cool tricks that viruses do to evade our immune system. Few years ahead full of viruses!🤓

    26 replies 7 retweets 394 likes
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  2. Retweeted
    58 minutes ago

    Seek shelter Guilford. Possible tornado moving in from Branford

    Watching this signature in Branford. Brief tornado possible
    5 retweets 12 likes
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  3. Retweeted
    1 hour ago

    No kidding. Very impressive tornado event on Long Island now.

    The Great Long Island Tornado Outbreak of 2021
    2 replies 8 retweets 29 likes
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  4. 3 hours ago

    Enjoying these colors after getting my flu shot... such a blessing.

    18 likes
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  5. Retweeted
    4 hours ago

    And very good evidence of frequent over spill of bat viruses into game species Oh and some clear evidence zoonotic transfer of human viruses into animals.

    2 replies 1 retweet 20 likes
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  6. Nov 12

    Nothing better than a rainy Fall morning with coffee to start with a new cloning design.

    10 likes
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  7. Retweeted
    Nov 11

    We are hiring!!! Our lab is looking for a highly motivated and curious Technician to help us understand the mechanisms controlling human antiviral pathways and the evolutionary forces that drove their emergence. Details/apply👇🏼

    3 replies 97 retweets 109 likes
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  8. Nov 11

    We finally received viruses that we were waiting for a while and I'm sooo excited!

    1 reply 14 likes
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  9. Retweeted
    Nov 11

    Our PI, , asked us to start incorporating a teachable moment into our lab meeting presentations where we talk about a technique, a virology principle, etc. So naturally I talked about plaque purifying virus, because who doesn’t love a good throwback?

    1 retweet 26 likes
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  10. Retweeted
    Nov 10

    This study by et al. team shows that RIG-I agonist stem loop RNA (SLR) triggers potent antiviral defense against to prevent primary infection and clear chronic infection.

    2 replies 48 retweets 120 likes
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  11. Nov 10

    Thanks to the really cool study previously done by and this one, we can see how Nsp12 E802D in SARS-CoV-2 might arise upon RDV treatment in vitro and in vivo!

    3 likes
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  12. Nov 10

    Might be a bit biased, but this was my fav part of this study.😋Reverse genetics for coronaviruses is a bit complex but really exciting! 😁 Thanks to everyone that was involved in this!

    Since the genome of the patient’s virus contained many other mutations, we needed to know if the nsp12 E802D mutation was sufficient to confer remdesivir resistance. heroically synthesized E802D mutant and showed that it’s indeed the case. (7/)
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    1 reply 1 retweet 25 likes
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  13. Retweeted
    Nov 10

    Our latest study is about an immunocompromised patient with persistent COVID ➡️ treated with remdesivir but developed resistant mutation ➡️ was then cured by monoclonal Ab cocktail. Study by et al. (1/)

    22 replies 243 retweets 697 likes
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  14. Nov 9

    Loving these naps that are supposed to be of a "few min" but weirdly transformed to a "few hours". 🤨

    1 retweet 10 likes
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  15. Retweeted
    Nov 8
    Replying to

    SARS-CoV-2 can use chicken ACE2 when expressed on BHK cells (see fig 3c of ) but there are evidently other restrictions in chicken cells (fibroblasts, same paper). Big bird is just being cautious... No harm in that. I hope he's planning a flu jab too!

    1 reply 2 retweets 11 likes
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  16. Nov 9

    Morning walk to lab these days is just really nice.

    1 reply 1 retweet 30 likes
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  17. Nov 8

    I don't really like that its getting dark this early

    1 reply 16 likes
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  18. Retweeted
    Nov 7

    Fiery and city silhouette tonight in (short timelapse).

    4 replies 46 retweets 244 likes
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  19. Retweeted
    Nov 7

    Available DM Bernini’s Elephant, Piazza della Minerva (1667)

    2 replies 28 retweets 51 likes
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  20. Nov 7

    Fall in main campus never stops to amaze me.

    1 reply 4 retweets 69 likes
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  21. Retweeted
    Nov 3

    The next chapter of anti-Covid is about to start with pills that inactivate the virus, irrespective of variants. First will be Molnupiravir in a matter of weeks, then this one. Helping to get us onto an exit ramp.

    59 replies 571 retweets 1,780 likes
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