Marco Bocchio

@marco_bocchio

Neuroscientist in Cossart lab at , dad, organic gardener. alumnus.

Vrijeme pridruživanja: lipanj 2012.

Medijski sadržaj

  1. 23. lis 2019.

    11/ Finally, we imaged ebGABAs in vivo and found that these cells are among a minority of cells in the network that are activated by a variety of network states.

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  2. 23. lis 2019.

    10/ What about inhibition? Do ebGABAs show distinct inhibitory wiring? Indeed, we show that compared to random GABA cells they receive weak local inhibition (with very little inputs from PV+ neurons). Instead, they are mostly inhibited by long-range inputs from the medial septum.

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  3. 23. lis 2019.

    9/ Mapping ebGABAs' inputs with electrical or optogenetic stimulations, we found that these cells, unlike random GABA cells, receive little excitation by extra-hippocampal inputs. Instead, they are mostly recruited by intra-hippocampal ones.

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  4. 23. lis 2019.

    8/ EbGABAs' firing patterns ex vivo appear more similar to pyramidal cells than interneurons, with strong adaptation upon strong depolarizing inputs, mainly due to depolarization block.

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  5. 23. lis 2019.

    7/ We then examined ebGABAs in adulthood. Using immunohistochemical analysis and reconstruction of biotin-filled cells, we found that ebGABAs aren’t canonical interneurons. They express markers of long-range projecting cell types that target different brain areas.

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  6. 23. lis 2019.

    6/ First, we used large-scale calcium imaging in neonatal slices combined with stimulation ebGABAs using whole cell patch clamp. We found that stimulation of a single ebGABA (but not of random GABA cells) could modulate the network. Thus, ebGABAs exert a hub function even in CA1.

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  7. 9. sij 2019.

    Our first patch clamp study on human cortical neurons is finally out in . Great collaboration between Somogyi and Capogna labs at Oxford Pharmacology Dept and , and clinicians at JR Hospital and . 1/3

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  8. 15. ruj 2017.
  9. 16. velj 2017.

    The rules of /glutamate cotransmission in the . Thanks for the editorial!

  10. 9. lis 2016.

    Now in final version: Sleep and serotonin modulate nitric oxide synthase expressing neurons of the amygdala

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