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Example: differing input impedance and a less than perfect output on the synth could alter the frequency response or noise. A positive ABX result doesn't prove there's a fundamental difference, but a negative ABX result does prove there isn't one (at least on that test material).
That's one of the big advantages of digital: once we get things into the digital domain it's a *lot* easier to perfectly quantify all sources of distortion and noise when applying digital processing :-)
