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I’m principally interested in interacting with / observing SIA OSDP which is implemented as a serial 2 wire RS485 multi drop bus.
Right, so the question is whether you're talking to one or two devices with very short cables in a controlled tabletop lab scenario (then option 2 will probably work), or whether you need to talk to an actual bus with proper termination over a longer distance (then you need 1).
Probably 1, for the scenarios I’d like to experiment with.
In that case, you need something like this: https://www.sparkfun.com/products/10124 Wiring it directly to the Glasgow pins should work, then you just need the TX enable feature. Set Glasgow to 3.3V mode and it will supply power to it, no extra hardware needed.
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