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Probably profiles for when I want strict separation (largely my Chromium VPN proxy profile, and the random testing profile), and MACs for multi-login use (which I have lots of Chromium profiles for).
The "open in container" thing seems very helpful, because what I found happened often in Chromium was that I'd start at $loggedinservice which was the intent of that profile, but then veer off into completely unrelated pages that had no real reason to be in that profile.
