This is pretty incredible. Vaccine makers suggesting the change in U.K. policy on vaccine dose sequencing is potentially hugely flawed. Are we snatching defeat out of the jaws of victory?https://twitter.com/BenKentish/status/1344584306589638656 …
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Pfizer is a 2 dose vaccine. In the trial some participants caught the virus between getting the first and second dose and one dose was found to be 52% effective.
Almost everyone who caught the virus after the first dose caught it within the first ten days, when you would not expect much if any immunity. Between 10 and 21 days it was nearly as effective as in the period following the second dose.
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The difference is big. https://www.bmj.com/content/371/bmj.m4826 …
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But as
@macrocephalopod said - that’s all about timing. Those cases were in the short period after first dose and before we’d expect it to be working anyway. There’s no evidence about rates after would expect immunity. - Show replies
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