I read the claim recently that compounds used recreationally are unusually likely to have therapeutic effects compared to random chemical
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I think the actual explanation is something like this: 1. Druggies are trying to feel good specifically (positive affect, interestingness)
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2. Pharma is trying to “treat constructs” but what consumers actually care about is feeling good and nothing else matters much
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Mental illness constructs aren’t actually what people (consumers/patients) care about, they care about feeling shitty or not
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Since DSM tends to have “clinically significant distress” thresholds for disorders you should be able to knock them all out by fixing that
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also ugghh i'm disappointed this poast doesn't touch the third rail of using opioids (which is absolutely and incontrovertibly trad, by the way) for treatment of suicidality even though there's evidence that it actually works lol https://ajp.psychiatryonline.org/doi/abs/10.1176/appi.ajp.2015.15040535?journalCode=ajp …
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yeah I wrote a whole chapter of a science book about that lol
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this is also related to the thing where pharmaceutical companies want to get similar actions as Illegal Drug Molecules whilst not using the exact same molecules so they have to tinker and end up getting something shitty and not as effective and sometimes the clinical trials kill.
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"The same thing but not addictive" (i.e. with orders of magnitude worse side effects)
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