Lisa Jarvis

@lisamjarvis

biotech/pharma reporter for . bit 'o science, bit 'o business. drug discovery, rare diseases, R&D, med chem, She/her

chicago
Vrijeme pridruživanja: listopad 2009.

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  1. Prikvačeni tweet
    23. ruj 2019.

    The first wave of KRAS G12C inhibitors are in the clinic--my long read on how chemists finally cracked this tough cancer target & what that work may (or may not) teach us about drugging the other RAS mutants:

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  2. proslijedio/la je Tweet

    Yes, it’s for ! Interesting finding that Tamiflu (combined with HIV protease inhibitors) inhibits replication. Corona doesn’t have sialidase but hemagglutinin/esterase (HE) (from related SARS) has hydrophobic pocket where pentanyl ether could bind.

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  3. proslijedio/la je Tweet
    5. velj
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  4. proslijedio/la je Tweet
    5. velj

    . is one of the best scientists of our time. This outstandingly-written profile by reflects Carolyn's sharpness, and infects you with her enthusiasm and passion for chemistry. Give it a read. It's *really* good.

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  5. 5. velj

    Also, if you aren't following for his excellent breakdowns of these AI in drug discovery papers, you're missing out.

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  6. 5. velj
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  7. 4. velj

    Ooh, look what just arrived on my doorstep!

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  8. 4. velj

    I've written/deleted many comments on this bc the lack of representation (not Adam's fault!) is so irksome. But I'm also not ready to cast this tableau until technologies like CRISPR and gene therapy have fully matured. That said: my great grandpa worked on Mount Rushmore!

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  9. 4. velj

    My cousin's daughter reports that at her caucus site, a Tulsi Gabbard supporter did a hog call. Democracy in action!

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  10. proslijedio/la je Tweet
    4. velj

    iowa caucus system -- takes a long time -- disenfranchises people -- prone to errors having paul, prue, and sandi from great british bake off just choose their favorite -- quick -- you dont have to talk to your neighbors -- never been wrong

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  11. 4. velj
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  12. 3. velj

    In summary, you have two months left to tell us about your brilliant colleagues and friends! Here's that form again:

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  13. 3. velj

    Each year, it gets tougher to winnow down to 12 because so many of you are so darned talented. If your candidate wasn’t picked, don’t despair! You’ve still put their work on the radar of our intrepid reporting team. So give us your best ideas for who we should be watching!

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  14. 3. velj

    Keep us updated: We reconsider nominees who made our short list in the previous year, but if a scientist has done something remarkable in the interim (came out w/important paper, started a company, designed a drug that went into the clinic, etc), do resubmit a nomination!

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  15. 3. velj

    Quality over quantity: While we understand the impulse to “campaign” for a certain researcher, two or three high quality nominations is far more helpful than 10-20 nominations that repeat the same information.

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  16. 3. velj

    Crafting your brief pitch: Our goal is to highlight scientists working on the world’s most vexing problems. When highlighting why your nominee is worthy, it's SO helpful to connect their research to the bigger picture: what problem is this solving in science or for humanity?

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  17. 3. velj

    Eligibility part 2: We've had a lot of questions in years past on the age cutoff. It is 42, but *we make exceptions* for people who have taken pauses or have switched careers

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  18. 3. velj

    Eligibility: -Academics *must be pre-tenure* (we occasionally consider exceptional grad students & postdocs) -Industry scientists should be <10 yrs out of postdoc -We seek a diverse, global group (more on that: )

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  19. 3. velj

    🚨 Nominations for ’s Talented 12 Class if 2020 are open until April 6th 🚨 (see here: ) I get a lot of questions about how to make a strong pitch, so wanted to give a few tips. Thread time!

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  20. 3. velj

    With reports of a clinical trial in Wuhan to study Gilead's remdesivir's effectiveness against coronavirus, here's my look at how the drug was discovered amid the 2014 Ebola outbreak :

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  21. 3. velj

    When you've gotten up at 4:45am to register your kid for summer camp and the coffee just won't kick in...

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