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Excited to see our Relate paper for genealogy estimation out today, alongside
@jeromekelleher et al’s tsinfer paper! https://www.nature.com/articles/s41588-019-0484-x … Thanks@simon_r_myers, this has been (and still is) a really fun project!Show this threadThanks. Twitter will use this to make your timeline better. UndoUndo -
Leo Speidel Retweeted
Great start to the
#wpsg2020 day with a talk by Simon Myers and@leo_speidel on the coalescent and the inference of genome-wide genealogies.pic.twitter.com/xT2teYvOsZ
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Leo Speidel Retweeted
Our preprint on ancestral haplotype reconstruction is out (and associated code "thread" https://github.com/mathiesonlab/thread …). Feedback welcome!https://twitter.com/biorxivpreprint/status/1217986491567263744 …
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Leo Speidel Retweeted
Latest paper from our group -- review of new methods for inferring positive selection, led by Hussein Hejase and
@ndukler (sorry, paywall).https://www.cell.com/trends/genetics/fulltext/S0168-9525(19)30269-0 …Thanks. Twitter will use this to make your timeline better. UndoUndo -
Leo Speidel Retweeted
My PhD thesis is submitted - it’s officially Christmas now

pic.twitter.com/7YpbS0FiwV
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Some positive news in UK is I passed my PhD viva, thanks
@simon_r_myers, Pier Palamara and@richard_durbin! (not looking great otherwise..)pic.twitter.com/rN328gAhz2
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Leo Speidel Retweeted
Thanks to Zach Fuller (
@zl_fuller), in collaboration with@heatshok,@LineKBay and many others, here is our first foray into precision medicine for corals:https://www.biorxiv.org/content/10.1101/867754v1 …Show this threadThanks. Twitter will use this to make your timeline better. UndoUndo -
Leo Speidel Retweeted
Plus several opportunities to join our department as a PhD student. Application period open again, deadlines in January. LIDo BBSRC DTP http://lido-dtp.ac.uk UCL-Birkbeck MRC DTP https://ucl.ac.uk/mrc-dtp/ London NERC DTP https://london-nerc-dtp.org Check out my projects!https://twitter.com/AidaAndres/status/1072474404439904256 …
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Leo Speidel Retweeted
Most pleased to announce that I have moved to The Institute Pasteur Shanghai, http://english.shanghaipasteur.cas.cn/ and my group is hiring at all levels. http://www.ips.ac.cn/qt2016/zp2016/201912/t20191203_5448659.html … 1/10
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Leo Speidel Retweeted
Felix Wu's work comparing sex-specific germline mutation rates in baboons to humans:https://www.biorxiv.org/content/10.1101/844910v1 …
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Leo Speidel Retweeted
We are looking for a postdoctoral researcher interested in complex trait evolution and ancient genomes to join our lab
@TheCrick. Application link -> https://my.corehr.com/pls/frckrecruit/erq_jobspec_version_4.display_form?p_company=1&p_internal_external=E&p_display_in_irish=N&p_applicant_no=&p_recruitment_id=012707&p_process_type=&p_form_profile_detail=&p_display_apply_ind=Y&p_refresh_search=Y …pic.twitter.com/allmd7XaI6
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Leo Speidel Retweeted
Another ZCWPW1 paper https://doi.org/10.1101/836023 , here from the Liu group, has hit biorXiv! That makes 3 in the last fortnight, with our preprint https://doi.org/10.1101/821678 and the
@todd_macfarlan preprint https://doi.org/10.1101/821603 . Hopefully this gene is feeling properly loved at last.Thanks. Twitter will use this to make your timeline better. UndoUndo -
Leo Speidel Retweeted
Here’s a preprint for a review we wrote on insights we can gain about past social practices and cultures from ancient DNA.
@siko76@bitesizeDNA Comments / suggestions welcome! https://arxiv.org/abs/1911.00755 pic.twitter.com/pwRnj42FYd
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Leo Speidel Retweeted
Summary of Relate and tsinfer in
@naturemethods this month:https://www.nature.com/articles/s41592-019-0639-9 …Thanks. Twitter will use this to make your timeline better. UndoUndo -
Leo Speidel Retweeted
Our new paper on ZCWPW1, now on bioRxiv! http://biorxiv.org/cgi/content/short/821678v1 …https://twitter.com/DanielJohnWells/status/1189612805181378561 …
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Leo Speidel Retweeted
PRDM9 deposits two histone marks, but what recognises them? Read our new preprint about ZCWPW1! https://www.biorxiv.org/content/10.1101/821678v1 …pic.twitter.com/2WFbevzJv6
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Leo Speidel Retweeted
Our paper on protein model quality assessment is out today in
@PLOSONE! RFQAmodel is a random forest classifier that combines existing quality assessment methods with contact map alignment scores to identify models in the correct fold:https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0218149 …Show this threadThanks. Twitter will use this to make your timeline better. UndoUndo -
Leo Speidel Retweeted
My two cents on direct-to-consumer testing of rare, potentially pathogenic variants. Even if the accuracy of a test for a particular mutation appears to be very high, a positive result should still be interpreted with caution. Insights from ol' Thomas Bayes:pic.twitter.com/rWCKDXtSjY
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Leo Speidel Retweeted
If you are interested in our method for leveraging whole-genome genealogies to disentangle the fitness effects of genetically-correlated polygenic traits, come see my poster (2385) today 2-3pm
#ASHG19 Fun work with@ras_nielsen and Noah Zaitlen!Thanks. Twitter will use this to make your timeline better. UndoUndo -
Leo Speidel Retweeted
Last chance to apply! Join the welcoming
#tskit open source community and help to lead it to exciting new places!https://twitter.com/jeromekelleher/status/1172540795527864321 …Thanks. Twitter will use this to make your timeline better. UndoUndo -
Leo Speidel Retweeted
Genotype imputation using the Positional Burrows Wheeler Transform http://biorxiv.org/cgi/content/short/797944v1 …
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