Leo Speidel

@leo_speidel

Postdoc at the Dept of Statistics, University of Oxford, working on Statistical Genomics.

Joined January 2015

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  1. Pinned Tweet
    2 Sep 2019

    Excited to see our Relate paper for genealogy estimation out today, alongside et al’s tsinfer paper! Thanks , this has been (and still is) a really fun project!

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  2. Retweeted
    Jan 24

    Great start to the day with a talk by Simon Myers and on the coalescent and the inference of genome-wide genealogies.

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  3. Retweeted
    Jan 18

    Our preprint on ancestral haplotype reconstruction is out (and associated code "thread" ). Feedback welcome!

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  4. Retweeted
    Jan 19

    Latest paper from our group -- review of new methods for inferring positive selection, led by Hussein Hejase and (sorry, paywall).

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  5. Retweeted
    20 Dec 2019

    My PhD thesis is submitted - it’s officially Christmas now 🎄🥂

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  6. 12 Dec 2019

    Some positive news in UK is I passed my PhD viva, thanks , Pier Palamara and ! (not looking great otherwise..)

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  7. Retweeted
    6 Dec 2019

    Thanks to Zach Fuller (), in collaboration with , and many others, here is our first foray into precision medicine for corals:

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  8. Retweeted
    6 Dec 2019

    Plus several opportunities to join our department as a PhD student. Application period open again, deadlines in January. LIDo BBSRC DTP UCL-Birkbeck MRC DTP London NERC DTP Check out my projects!

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  9. Retweeted
    3 Dec 2019

    Most pleased to announce that I have moved to The Institute Pasteur Shanghai, and my group is hiring at all levels. 1/10

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  10. Retweeted
    17 Nov 2019

    Felix Wu's work comparing sex-specific germline mutation rates in baboons to humans:

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  12. Retweeted
    8 Nov 2019

    Another ZCWPW1 paper , here from the Liu group, has hit biorXiv! That makes 3 in the last fortnight, with our preprint and the preprint . Hopefully this gene is feeling properly loved at last.

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  13. Retweeted
    4 Nov 2019

    Here’s a preprint for a review we wrote on insights we can gain about past social practices and cultures from ancient DNA. Comments / suggestions welcome!

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  14. Retweeted
    1 Nov 2019

    Summary of Relate and tsinfer in this month:

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  15. Retweeted
    30 Oct 2019
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  16. Retweeted
    30 Oct 2019

    PRDM9 deposits two histone marks, but what recognises them? Read our new preprint about ZCWPW1!

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  17. Retweeted
    21 Oct 2019

    Our paper on protein model quality assessment is out today in ! RFQAmodel is a random forest classifier that combines existing quality assessment methods with contact map alignment scores to identify models in the correct fold:

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  18. Retweeted
    18 Oct 2019

    My two cents on direct-to-consumer testing of rare, potentially pathogenic variants. Even if the accuracy of a test for a particular mutation appears to be very high, a positive result should still be interpreted with caution. Insights from ol' Thomas Bayes:

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  19. Retweeted
    16 Oct 2019

    If you are interested in our method for leveraging whole-genome genealogies to disentangle the fitness effects of genetically-correlated polygenic traits, come see my poster (2385) today 2-3pm Fun work with and Noah Zaitlen!

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  20. Retweeted

    Last chance to apply! Join the welcoming open source community and help to lead it to exciting new places!

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  21. Retweeted
    9 Oct 2019

    Genotype imputation using the Positional Burrows Wheeler Transform

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