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Interesting case on DBS for genet. confirmed Chorea-Acanthocytosis from the team at
@BIDMChealth. DBS between GPe and putamen led to improvement of speech, swallowing and chorea, weight gain and improvements in daily living. http://doi.org/10.1159/000500951 …pic.twitter.com/zMHqEC7Xtr
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Very interesting case about GPe stimulation for insomnia with good results and work up by
@MayoRadiology team https://www.sciencedirect.com/science/article/pii/S0025619619310341 …pic.twitter.com/wq9ivsZWBO
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Lead DBS proslijedio/la je Tweet
A new era in brain modulation... https://twitter.com/RMarkRichardson/status/1223367511351099392 …pic.twitter.com/nE5N1z0092
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Lead DBS proslijedio/la je Tweet
Next milestones for open DBS imaging ! Great work from the
@leaddbs team.https://twitter.com/leaddbs/status/1220772801201803267 …
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Extraordinary has-it-all study with i) novel way to parcellate the thamalus based on MP2RAGE, ii) largest cohort of patients N=19 with LGS epilepsy iii) electrode reconstructions in CM nucleus, iv) micro-electrode recordings and v) rs-fMRI connectivity!

https://twitter.com/aaronsighed/status/1220988685807575040 …pic.twitter.com/2sE2OpCZ9Q
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It just became pretty easy to compare patient-specific electrode localizations to literature-based DBS targets within Lead-DBS.https://twitter.com/andreashorn_/status/1221048924376576000 …
0:40Hvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
Lead DBS proslijedio/la je Tweet
my paper is finally out in JNNP! we describe a new method for targeting the centromedian nucleus for deep brain stimulation using MP2RAGE MRI, intraop microelectrode recordings, and resting-state fMRI connectivity
@leaddbs@LGS_Foundationhttps://twitter.com/JNNP_BMJ/status/1220763510122196993 …Hvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
Lead-DBS v.2.3 is out now! A ton of news, all here: https://www.lead-dbs.org/?na=v&nk=1-ff6ea9928d&id=22 …
@NingfeiL@andreashorn_@simonoxen@neumann_wj@DembekTill@SvenjaTreu@FriederikeIrmen@b_alfatly@AndrewZalesky@yetianmed@DrBreaky@DaniSBassett@Xiaosong_He@FangChengYeh@agramfort@GerdTinkhauserpic.twitter.com/JiYI6tEiMY
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Lead DBS proslijedio/la je Tweet
So exciting to see that labs are using the
#100micronMRI template in@leaddbs! If people are interested in the native-space or MNI-coregistered datasets, they are at Dryad https://datadryad.org/stash/dataset/doi:10.5061/dryad.119f80q … and OpenNeuro https://openneuro.org/datasets/ds002179/versions/1.1.0 … Additional details: https://www.nature.com/articles/s41597-019-0254-8 …https://twitter.com/leaddbs/status/1217804446698221569 …
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Lead DBS proslijedio/la je Tweet
If you’re in Germany, conduct research related to Parkinson’s Disease and are looking to go abroad, consider applying for a fellowship with the Thiemann foundation!https://www.thiemannstiftung.de/projekte/thiemann-fellowship-2020/ …
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It's now possible to plan trajectories (for research purposes) and visualize them as electrodes of different type on the fly. Helpful for creating figures or literature-based electrodes.
#releaseSprint@andreashorn_@NingfeiL@simonoxen@DembekTillpic.twitter.com/RkwbxlndryHvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
From now on, volumes of tissue activated will be estimated in native space and ported to template on the fly in Lead-DBS. Also much more flexible parameters for VTAs in general. New release this Friday!
@NingfeiL@simonoxen@neumann_wj@FriederikeIrmen@qiangwangdr@DembekTillpic.twitter.com/PtbBoTj9Sk
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Interesting study by Hai Lin et al. that extracted connectiity of electrode localizations with random forrest classifiers to predict effective vs. ineffective DBS contacts with 85% accuracy in the validation group. https://onlinelibrary.wiley.com/doi/10.1002/hbm.24927 …pic.twitter.com/Q1cY2YtIOe
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Lead DBS proslijedio/la je Tweet
Study by
@SvenjaTreu introducing a tool for group level analyses in the deep brain stimulation imaging field

https://twitter.com/leaddbs/status/1217804446698221569 …
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Lead DBS proslijedio/la je Tweet
Comparison of data driven Connectome filtering (based on dMRI, A&B) with a holographic tract atlas by Petersen et al. recently published in
@NeuroCellPress give similar result of the hyperdirect pathway. https://www.cell.com/neuron/pdf/S0896-6273(19)30832-3.pdf …https://twitter.com/leaddbs/status/1217807093174013952 …
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Lead DBS proslijedio/la je Tweet
#deepbrainstimulation electrode location modeling & simulation imaging#opensource#githubhttps://twitter.com/leaddbs/status/1217804968733937665 …Hvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
Lead DBS proslijedio/la je Tweet
Overly happy and grateful for being part of this project! Check out this wonderful toolbox : https://www.biorxiv.org/content/10.1101/2020.01.14.904615v1 …https://twitter.com/leaddbs/status/1217804446698221569 …
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Finally, we estimate which fibertracts are exclusively connected with good responders, thus isolating the hyperdirect pathway in a data-driven fashion from a whole-brain connectome. Comparison with the Petersen tract atlas of the hyperdirect pathway.pic.twitter.com/KJakavMDoB
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We then explore connectivity, how structural connections to different cortical regions correlate with improvement. This figure done outside of
@leaddbs with Chris Rorden's excellent Surfice tool.pic.twitter.com/Hsej6t7wRj
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Some analyses in Lead group require group assignments, so we split the cohort in half to have the top responding half vs. the poorest responding half. Those have significantly different overlaps with the target structure (STN).pic.twitter.com/YNvUuQDVH1
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