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kimmaicutler's profile
Kim-Mai Cutler
Kim-Mai Cutler
Kim-Mai Cutler
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@kimmaicutler

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Kim-Mai CutlerVerified account

@kimmaicutler

Partner at @initialized. Previously @techcrunch. When life hands me lemons, I make tarte au citron.

San Francisco
medium.com/initialized-ca…
Joined April 2008

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    1. Stuart Buck‏ @stuartbuck1 May 19
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      Replying to @rivatez @kimmaicutler @rabois

      This meta-analysis seems unbiased: https://www.medrxiv.org/content/10.1101/2020.05.14.20101774v1 … Certainly better evidence than "See India"!

      2 replies 0 retweets 2 likes
    2. Riva‏Verified account @rivatez May 19
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      Replying to @stuartbuck1 @kimmaicutler @rabois

      Need to look at the timing of the delivery for each case they review, studies where they give it to already hospitalized / well developed cases should be discredited, whole point is it needs to be early

      1 reply 0 retweets 3 likes
    3. Riva‏Verified account @rivatez May 19
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      Replying to @rivatez @stuartbuck1 and

      And yes India is interesting - government intiative to give it as a prophylactic to medical workers and widespread usage in certain high density slums? sounds like the biggest global trial... not sure why you would want to ignore it

      1 reply 0 retweets 0 likes
    4. Stuart Buck‏ @stuartbuck1 May 19
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      Replying to @rivatez @kimmaicutler @rabois

      Without a counterfactual and without reliable testing data, I'm not sure what we can possibly learn from India here.

      1 reply 0 retweets 1 like
    5. Kim-Mai Cutler‏Verified account @kimmaicutler May 19
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      Replying to @stuartbuck1 @rivatez @rabois

      Seems like they shelved that plan too. https://abcnews.go.com/Health/wireStory/trumps-malaria-drug-combat-virus-spurs-india-boon-70758373 …pic.twitter.com/eC8oGifAz9

      2 replies 0 retweets 0 likes
    6. Riva‏Verified account @rivatez May 20
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      Replying to @kimmaicutler @stuartbuck1 @rabois

      Riva Retweeted James Todaro, MD

      here's some of those 'shelved plans' data coming through-https://twitter.com/JamesTodaroMD/status/1263148644556996610?s=20 …

      Riva added,

      James Todaro, MDVerified account @JamesTodaroMD
      India offered HCQ prophylaxis to 10,000 Mumbai policemen. About 4,500 routinely took HCQ, while 5,500 refused. RESULTS: HCQ group: 0 deaths Non-HCQ group: 9 deaths And those who contracted COVID-19 in the HCQ group had "mild attacks" h/t @niro60487270 https://timesofindia.indiatimes.com/city/mumbai/toll-climbs-to-9-cops-on-hcqs-spared-the-worst/articleshow/75845670.cms …
      1 reply 0 retweets 1 like
    7. Stuart Buck‏ @stuartbuck1 May 20
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      Replying to @rivatez @kimmaicutler

      This is nowhere near as good as a controlled experiment. People who adhere to treatment do better even when it's a placebo (they're more conscientious generally). Classic example from the medical literature (note the survival rates in the placebo group):https://pubmed.ncbi.nlm.nih.gov/6999345/ 

      1 reply 0 retweets 1 like
    8. Stuart Buck‏ @stuartbuck1 Jun 3
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      Replying to @stuartbuck1 @rivatez @kimmaicutler

      Randomized, placebo-controlled, double-blinded trial on early use of HCQ as a preventative: no benefit.https://www.washingtonpost.com/health/2020/06/03/hydroxychloroquine-clinical-trial-results/ …

      1 reply 0 retweets 0 likes
    9. Riva‏Verified account @rivatez Jun 3
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      Replying to @stuartbuck1 @kimmaicutler

      Sharing a WaPo article when the study isn’t even out yet? And considering both you and NEJM were touting a ‘nail in the coffin’ study that proved to be unbelievably fraudulent, I’ll wait to make up my own decisions :)

      1 reply 0 retweets 1 like
    10. Stuart Buck‏ @stuartbuck1 Jun 3
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      Replying to @rivatez @kimmaicutler

      Not me! :) I would never plug an observational study in the Lancet of all places (going at least back to the Andrew Wakefield vaccine study, they aren't that good at catching obvious errors).

      1 reply 0 retweets 0 likes
      Kim-Mai Cutler‏Verified account @kimmaicutler Jun 10
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      Replying to @stuartbuck1 @rivatez

      Sad.https://www.sciencemag.org/news/2020/06/three-big-studies-dim-hopes-hydroxychloroquine-can-treat-or-prevent-covid-19 …

      7:36 AM - 10 Jun 2020
      1 reply 0 retweets 0 likes
        1. Stuart Buck‏ @stuartbuck1 Jun 13
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          Replying to @kimmaicutler @rivatez

          Stuart Buck Retweeted Stuart Buck

          Sad #1: that HCQ doesn't work, as we could really use an effective treatment. Sad #2: the meta-cognitive failure in @rabois being so certain that the VC mentality is a useful way to approach clinical medicine.https://twitter.com/stuartbuck1/status/1243240228451647491 …

          Stuart Buck added,

          Stuart Buck @stuartbuck1
          In addition to what @Jabaluck has pointed out, I wonder if part of the problem with @rabois comments about RCTs is that some VCs become very successful by having good contrarian instincts and then getting lucky a few times. https://twitter.com/rabois/status/1243215225823744000 …
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