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kareem_carr's profile
🔥Kareem Carr🔥
🔥Kareem Carr🔥
 🔥Kareem Carr 🔥
@kareem_carr

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 🔥Kareem Carr 🔥

@kareem_carr

PhD student at @Harvard | Phd Life | Humor | Statistics | Society | DMs open: 1. say why you're DMing in the first text 2. I don't do free consulting

Cambridge, MA
instagram.com/kareemcarr/
Joined June 2013

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     🔥Kareem Carr 🔥‏ @kareem_carr Jun 22

    After an experiment, a subject matter expert examines the numbers and is now more sure of the hypothesis. A statistician examines the same data using the best techniques and finds no evidence that the hypothesis is true. Is it possible *BOTH* are right? #datascience #epitwitter

    7:36 AM - 22 Jun 2019
    • 5 Retweets
    • 8 Likes
    • 𝙴𝚛𝚒𝚌𝚊𝙷𝚘𝚎𝚐𝚎𝚎𝚂𝚝𝚎𝚞𝚜𝚜𝚒𝚎 olcan priya joseph Doctor_David manolo Adam Chess Koji_Tanaka Ellie Murray Rasu
    11 replies 5 retweets 8 likes
      1. New conversation
      2. Elea McDonnell Feit‏ @eleafeit Jun 22
        Replying to @kareem_carr @EpiEllie

        How could any amount of data have no evidence at all? The statistician must be wrong.

        2 replies 0 retweets 0 likes
      3.  🔥Kareem Carr 🔥‏ @kareem_carr Jun 22
        Replying to @eleafeit @EpiEllie

        Noise. Randomness.

        1 reply 0 retweets 2 likes
      4. Elea McDonnell Feit‏ @eleafeit Jun 22
        Replying to @kareem_carr @EpiEllie

        As a Bayesian, the only way I see that the experiment - even a noisy one - can provide exactly zero information about the hypothesis is if the experiment is completely unrelated to the hypothesis or otherwise fatally flawed.

        1 reply 0 retweets 4 likes
      5. Elea McDonnell Feit‏ @eleafeit Jun 22
        Replying to @eleafeit @kareem_carr @EpiEllie

        The SME is probably better than the statistician at detecting these types of flaws.

        1 reply 0 retweets 1 like
      6.  🔥Kareem Carr 🔥‏ @kareem_carr Jun 22
        Replying to @eleafeit @EpiEllie

        Two people argue about which pet is a more common: cats or dogs. They decide to go to a vet and see what animals come in. First, a ferret. Then an emu etc. By the end of the day, no cats or dogs. No information about the hypotheses. Reasonable experiment, but uncooperative data.

        1 reply 0 retweets 0 likes
      7. Elea McDonnell Feit‏ @eleafeit Jun 22
        Replying to @kareem_carr @EpiEllie

        Fair enough, but I would call that fatally flawed and I imagine the SME would be in a better position to know that ferrets and emus are unrelated and that this sampling frame selects on sickness. I could be wrong, of course. :)

        0 replies 0 retweets 1 like
      8. End of conversation
      1. New conversation
      2. Michael von Forstner‏ @ForstnerVon Jun 22
        Replying to @kareem_carr @EpiEllie

        Both can be right as "being more confident about the hypothesis" is definitely not the same as "statistically showing a hypothesis to be true"

        1 reply 1 retweet 2 likes
      3.  🔥Kareem Carr 🔥‏ @kareem_carr Jun 22
        Replying to @ForstnerVon @EpiEllie

        What do you think is the difference?

        1 reply 0 retweets 0 likes
      4. Michael von Forstner‏ @ForstnerVon Jun 22
        Replying to @kareem_carr @EpiEllie

        Wearing my oncologist hat, I will treat a patient if I see a clinically relevant trend in outcomes even if my pharmacoepi hat tells me the null hypothesis is statistically not ruled out. Decision making under epistemological uncertainty is different from statistical reasoning.

        1 reply 2 retweets 7 likes
      5. Michael von Forstner‏ @ForstnerVon Jun 22
        Replying to @ForstnerVon @kareem_carr @EpiEllie

        Yet the data supporting either decision making process are the same.

        0 replies 1 retweet 1 like
      6. End of conversation
      1. New conversation
      2. Stephen Olivier‏ @Stephen_0livier Jun 22
        Replying to @kareem_carr

        What does "...finds no evidence that the hypothesis is true..." mean?

        1 reply 0 retweets 1 like
      3.  🔥Kareem Carr 🔥‏ @kareem_carr Jun 22
        Replying to @Stephen_0livier

        Can you elaborate? Maybe I'm missing something and you can help me come up with a better version of the question.

        1 reply 0 retweets 0 likes
      4. Stephen Olivier‏ @Stephen_0livier Jun 22
        Replying to @kareem_carr

        I suppose it boils down to what you mean by "best techniques". How did the statistician decide there was no evidence? I'm presuming they didn't just decide based on statistical significance.

        0 replies 0 retweets 0 likes
      5. End of conversation
      1. Chris Shurtleff‏ @chrisashurt Jun 22
        Replying to @kareem_carr

        I put 'Yes' but I want to be on the record as saying I am deeply skeptical of expert opinion that isn't validated by statistical methods. The 'Yes' is because it's pretty feasible that the expert's priors are right, but a more conservative prior finds insufficient support.

        0 replies 1 retweet 6 likes
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      1. New conversation
      2. Mattia Prosperi‏ @MasahikoKim Jun 22
        Replying to @kareem_carr @EpiEllie

        The subject matter expert is a statistician, innit?

        1 reply 0 retweets 2 likes
      3. Michael Barrowman‏ @MyKo101AB Jun 22
        Replying to @MasahikoKim @kareem_carr

        pic.twitter.com/O5riGfoC0s

        0 replies 0 retweets 1 like
      4. End of conversation
      1. Tom Kelly ケリー・トム‏ @tomkXY Jun 22
        Replying to @kareem_carr

        A domain expert will be much more aware of other corroborating evidence and what we should expect from the experiment. If the controls behave as expected for example. We should avoid p-hacking and so on but we mustn’t dismiss the expertise of those who know the system better.

        0 replies 0 retweets 1 like
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      1. Sighsyphus‏ @Sighsyphus Jun 22
        Replying to @kareem_carr

        Amateur here: but doesn’t your statement still allow for the presence of evidence against competing hypotheses (which the statistician may be simply unaware of)? Guess that’s not what you mean to ask with the hypothetical though

        0 replies 0 retweets 1 like
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      1. Ollie Östlund‏ @OstlundOllie Jun 23
        Replying to @kareem_carr

        Sounds like you are just describing a bayesian and frequentist analysis. Both are right in their own framework, the bayesian because the expert believes in it, the frequentist because there is no evidence. To find work for the statistician, you can downdate to find the prior.

        0 replies 0 retweets 0 likes
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      1. Nathan Brouwer‏ @lobrowR Jun 22
        Replying to @kareem_carr

        What's the sample size? Power? Alpha? The prior? Cost of making a mistake?

        0 replies 0 retweets 0 likes
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