Like Pfizer/Biontech last week, this is an interim analysis of an ongoing study and this is a press release not a peer-reviewed article.
But this is one more indication that the first generation of #covid19 vaccines will work and work better than most had hoped for.
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Particularly interesting that Moderna also looked at severe cases of
#covid19: For this interim analysis there were 11 severe cases, all of them in the placebo group. This does not mean that the vaccine prevents severe cases, but at least it is consistent with that.Show this thread -
Safety also looks good for now: "The interim analysis included a concurrent review of the available Phase 3 COVE study safety data by the DSMB, which did not report any significant safety concerns."
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To give an idea, here are severe events they reported with frequency of 2% or more after second dose: fatigue (9.7%) myalgia (8.9%) arthralgia (5.2%) headache (4.5%) pain (4.1%) erythema/redness at the injection site (2.0%)
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All the usual caveats apply, of course: We don’t know how long immunity lasts We don’t know whether vaccine prevents transmission Rare serious adverse events can still be found Manufacturing vaccine takes time Distribution will be a challenge ...
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But all the indications here point to this: Vaccines against
#covid19 are coming. They are coming at an unprecedented pace. They are likely to be highly efficacious at least at preventing disease. It is up to us to hold the line this winter against this virusShow this thread
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mRNA vaccines are quite unknown to the public: a plain field for conspiracists. Would be nice if specialists could prepare very accessible and complete "mRNA vaccine for dummies" to preempt "mad theories" and prevent media from telling idiocies before the vaccines are out

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This is an extremely good point which should be taken on by some respected source ASAP. Maybe
@kakape could look into it?
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Hallo, you can read it here:
@kakape: Good vaccine news continues:@moderna_tx just announced its vaccine has shown 94,5% efficacy. In the study of… https://threadreaderapp.com/thread/1328309666091311106.html … Have a good day.
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