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kakape's profile
Kai Kupferschmidt
Kai Kupferschmidt
Kai Kupferschmidt
Verified account
@kakape

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Kai KupferschmidtVerified account

@kakape

science journalist. molecular biologist. curious. contributing correspondent at @sciencemagazine part of @pandemiapodcast, all things #blue

Berlin, Germany
sciencemag.org/author/kai-kup…
Joined June 2009

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    Kai Kupferschmidt‏Verified account @kakape 16 Nov 2020

    Good vaccine news continues: @moderna_tx just announced its vaccine has shown 94,5% efficacy. In the study of more than 30,000 participants, 95 #covid19 cases were observed (starting two weeks after second dose): 90 in placebo group 5 in vaccine group https://buff.ly/3puVGK6 

    4:11 AM - 16 Nov 2020
    • 164 Retweets
    • 384 Likes
    • Leeam Azoulay Suzanne Stephen Dedalus Ruth Coetzee InesR 🔴 Gordian Balaster 💉💉💉 Covid Expert Tweets TatjanaH Juan Moreno G. Loygorri
    5 replies 164 retweets 384 likes
      1. New conversation
      2. Kai Kupferschmidt‏Verified account @kakape 16 Nov 2020

        Like Pfizer/Biontech last week, this is an interim analysis of an ongoing study and this is a press release not a peer-reviewed article. But this is one more indication that the first generation of #covid19 vaccines will work and work better than most had hoped for.

        2 replies 26 retweets 100 likes
        Show this thread
      3. Kai Kupferschmidt‏Verified account @kakape 16 Nov 2020

        Particularly interesting that Moderna also looked at severe cases of #covid19: For this interim analysis there were 11 severe cases, all of them in the placebo group. This does not mean that the vaccine prevents severe cases, but at least it is consistent with that.

        2 replies 15 retweets 73 likes
        Show this thread
      4. Kai Kupferschmidt‏Verified account @kakape 16 Nov 2020

        Safety also looks good for now: "The interim analysis included a concurrent review of the available Phase 3 COVE study safety data by the DSMB, which did not report any significant safety concerns."

        1 reply 7 retweets 39 likes
        Show this thread
      5. Kai Kupferschmidt‏Verified account @kakape 16 Nov 2020

        To give an idea, here are severe events they reported with frequency of 2% or more after second dose: fatigue (9.7%) myalgia (8.9%) arthralgia (5.2%) headache (4.5%) pain (4.1%) erythema/redness at the injection site (2.0%)

        5 replies 15 retweets 65 likes
        Show this thread
      6. Kai Kupferschmidt‏Verified account @kakape 16 Nov 2020

        All the usual caveats apply, of course: We don’t know how long immunity lasts We don’t know whether vaccine prevents transmission Rare serious adverse events can still be found Manufacturing vaccine takes time Distribution will be a challenge ...

        4 replies 26 retweets 102 likes
        Show this thread
      7. Kai Kupferschmidt‏Verified account @kakape 16 Nov 2020

        But all the indications here point to this: Vaccines against #covid19 are coming. They are coming at an unprecedented pace. They are likely to be highly efficacious at least at preventing disease. It is up to us to hold the line this winter against this virus

        2 replies 45 retweets 168 likes
        Show this thread
      8. End of conversation
      1. New conversation
      2. Merle Christophe‏ @MerleChristoph4 16 Nov 2020
        Replying to @kakape @moderna_tx

        mRNA vaccines are quite unknown to the public: a plain field for conspiracists. Would be nice if specialists could prepare very accessible and complete "mRNA vaccine for dummies" to preempt "mad theories" and prevent media from telling idiocies before the vaccines are out 🙏

        4 replies 2 retweets 30 likes
      3. HaraldSch‏ @HaraldSchER 16 Nov 2020
        Replying to @MerleChristoph4 @kakape @moderna_tx

        This is an extremely good point which should be taken on by some respected source ASAP. Maybe @kakape could look into it?

        1 reply 0 retweets 10 likes
      4. End of conversation
      1. New conversation
      2. Aviva Gabriel‏ @avivajazz 16 Nov 2020
        Replying to @kakape @moderna_tx

        @threadreaderapp unroll

        1 reply 0 retweets 0 likes
      3. Thread Reader App‏ @threadreaderapp 16 Nov 2020
        Replying to @avivajazz

        Hallo, you can read it here: @kakape: Good vaccine news continues: @moderna_tx just announced its vaccine has shown 94,5% efficacy. In the study of… https://threadreaderapp.com/thread/1328309666091311106.html … Have a good day. 🤖

        0 replies 0 retweets 0 likes
      4. End of conversation

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