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PegahKA
@ka_pegah
Evolving Neurologist | Former Neurophysiology Research Fellow| Movement & Cognition 🧠| Art & Philosophy Enthusiast 🌊
Los Angeles, CAJoined March 2018

PegahKA’s Tweets

Sometimes it’s just impossible to be Aristotelian. Sometimes it’s just as simple and vague as it is; « WHERE I AM FROM, IF YOU PUT IT IN A POT, SEASON IT RIGHT AND COOK IT, THEY CALL IT A GUMBO, AND IF YOU FIX IT RIGHT, IT’S GOOD!» Buddy Guy
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A few weeks ago, we released a preprint on propofol anesthesia's effects on alpha (~10 Hz) oscillations in human thalamocortical networks. This short study is the culmination of over a decade's work, made possible by two datasets and a number of technical advances. 🧵:
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and by inducing a non-physiological inhibition of the prefrontal-mediodorsal thalamocortical subnetwork, which restricts its activity to alpha and low-beta bands and interferes with top-down processes.
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We propose that propofol induced oscillatory dynamics may disrupt conscious processing by placing posterior thalamocortical subnetworks in a hyperpolarized state, which degrades feedforward sensory contents and renders them inaccessible to prefrontal oscillatory feedback;
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If you are interested in the brain oscillatory dynamics in altered states of consciousness, my amazing friends and ex lab mates, & characterized the unique alternating gamma slow-delta dynamics of ketamine anesthesia: journals.plos.org/ploscompbiol/a
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Indeed very happy to see this co-first authored work from my #postdoc at @MIT_Picower is out in @PLOSCompBiol. Please check out the paper and please share in relevant circles. twitter.com/IndieGarwood/s…
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I pushed my first tPA today I am not gonna lie, it was quite similar to the saline flush, except for feeling a much greater responsibility. What is amazing though, is that moment of collectively making a final decision in the face of all uncertainties.
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Thalamocortical afferents (TCA) carry information important for motor function. Mirela Simon, MD, MSc, of , & Brian Nahed, MD, MSc, of @MGHNeurolog, & colleagues describe a new technique for TCA monitoring and mapping via cortical recordings advances.massgeneral.org/neuro/journal.
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Hey NY, until next time…! Finished the intern year, in an extraordinary city, in an extraordinary time! It’s about time to run the stroke code! 🧠
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Last year on the 31st, in the midst of the residency application, I tweeted this. The recital, the one thing I was certain about, got cancelled because of the pandemic! But here I am, on the 31st again, enjoying a night shift in the ICU! It’s all about the UNCERTAINTY!
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Embracing all the uncertainties of 2020, there is at least one thing I am certain about; I just found out I am going to @ReneeFleming’s recital, hearing her magical voice live, for the first time!
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I highly encourage those who are interested in the limits and determinants of the working memory capacity to study the medicine interns on COVID floors. I am amazed by the number of tasks I am « consciously » juggling at once! 🧠〰️
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Thank you for sharing our work, at , with the society; Brain oscillatory states could link the neurobiological processes at the cellular level to the cognitive level! 〰️🧠
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🔴 Intraop burst suppression & postop delirium are correlated-authors showed low anesth-induced frontal alpha power associated with burst suppression, independent of age: low frontal alpha power could be a marker of a “vulnerable brain” @ka_pegah @_RayShao journals.lww.com/anesthesia-ana
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