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Jan Willem de Gee proslijedio/la je Tweet
New preprint about choice predictive feedforward/back signals in V1 (https://www.biorxiv.org/content/10.1101/2020.02.01.929893v2 …). Joint work with an amazing group of people:
@neuromurphy, Florent Meyniel and Tobias Donner. And of course@donner_lab!Hvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
Jan Willem de Gee proslijedio/la je Tweet
New
#preprint out on@biorxiv! \w@neuromurphy,@kobedesender, Nicole de Ru & Sander Nieuwenhuis, we show that temporal expectation enhances perception by speeding up the the decision process onset without affecting its evolution!#tweeprint below (1/10)http://bit.ly/2vL0ovXPrikaži ovu nitHvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
Jan Willem de Gee proslijedio/la je Tweet
Interested in decision-making, evidence accumulation, normative or circuit models, oscillations, cortical hierarchy, feedback, or brainstem arousal systems? Check out our new paper on
@biorxivpreprint (https://www.biorxiv.org/content/10.1101/2020.01.29.924795v1 …)! Led by@neuromurphy, summary below. (1/11)Prikaži ovu nitHvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
Jan Willem de Gee proslijedio/la je Tweet
Today I will be teaching my undergrad course "How to build a brain from scratch" for the 2nd year running. I've put the materials online - include a document with all lecture slides and notes, which is about as long as a decent novel. Enjoy!https://humaninformationprocessing.com/teaching/
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Jan Willem de Gee proslijedio/la je Tweet
Updated our manuscript on viral manipulation of interneurons from mice to humans. Now with scATACseq-based enhancer selection and 4 new PV-specific enhancers with exquisite specificity for distinct regions of the brain : https://www.biorxiv.org/content/10.1101/808170v2 …
@StanleyCenter@broadinstituteHvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
Jan Willem de Gee proslijedio/la je Tweet
Excited to share our latest work : mice display several key behavioral and neural signatures of visual spatial attention. Great job by
@AndersonMSpeed,@JosephPDRosario Full (open access) article!
https://www.nature.com/articles/s41467-020-14355-4 …Hvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
Jan Willem de Gee proslijedio/la je Tweet
I'm very proud and excited to present to you: a team science approach to reproducibly studying decision-making! https://doi.org/10.1101/2020.01.17.909838 … Want to know what it's been like to work on this? Behind-the-scenes

1/manyhttps://twitter.com/IntlBrainLab/status/1218585772812570624 …
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Jan Willem de Gee proslijedio/la je Tweet
Modulation of Coordinated Activity across Cortical Layers by Plasticity of Inhibitory Synapses https://www.cell.com/cell-reports/fulltext/S2211-1247(19)31709-7?rss=yes …pic.twitter.com/YifjFV3a6v
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Jan Willem de Gee proslijedio/la je Tweet
New preprint! We made bright, tunable, far-red calcium and voltage indicators. Great collaboration
@HHMIJanelia between chemistry and protein engineering with@Abdelfattah__A and many others in the labs of@rhodamine110 and@ERSchreiter. Check it out!https://www.biorxiv.org/content/10.1101/2020.01.08.898783v1 …Hvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
Jan Willem de Gee proslijedio/la je Tweet
I am super proud to share this work done in collaboration with Taylor Schmitz, Judes Poirier and Hermona Soreq, linking basal forebrain atrophy to neuroinflammation and amyloid/tau pathology in the very earliest stages of Alzheimer's diseasehttps://doi.org/10.1523/JNEUROSCI.1184-19.2019 …
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Jan Willem de Gee proslijedio/la je Tweet
Mechanisms underlying gain modulation in the cortex https://www.nature.com/articles/s41583-019-0253-y …pic.twitter.com/OMB3RNwCVh
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Thanks to all co-authors, including:
@donner_lab@McGinleyLab@AnneEUrai@k_tsetsos@neuro_klooster@NWilming@colizoli@DavidAMcCormick@Tknapen !!Prikaži ovu nitHvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
11/11 In sum, when decisions are made in the face of uncertainty, tracking phasic arousal signals and the history of choices may be just as important for predicting choice behavior as tracking the objective evidence gathered from the outside world.
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10/11 We also found that evidence accumulation process is not only driven by the momentary evidence, bias, and arousal, but also by previous choices.
@eLife:https://elifesciences.org/articles/46331Prikaži ovu nitHvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
9/11 We also found that pupil-linked phasic arousal is recruited in relation to key computational variables such as
#uncertainty and#surprise.@SciReports:https://www.nature.com/articles/s41598-018-31985-3 …Prikaži ovu nitHvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
8/11 Repeating the same yes/no experiment during simultaneous MEG and pupillometry showed that the bias suppression is mediated by the arousal-related shaping of choice-predictive alpha-band activity in visual regions, including primary visual cortex.pic.twitter.com/rWrfvMRZs3
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7/11 We then showed that the arousal-linked bias suppression in evidence accumulation is a general principle: it occurs in a range of decision-making tasks (across sensory domains and when based on memory) and across species (humans and mice).
@bioRxiv: https://www.biorxiv.org/content/10.1101/447656v3 …pic.twitter.com/hW8sJZF5op
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6/11 Behavioral modeling indicated that subject’s evidence accumulation process was least biased on trials characterized by large pupil-linked arousal responses.
@eLife: https://elifesciences.org/articles/23232 pic.twitter.com/HvKHGiyKW1
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5/11 Repeating the same experiment during simultaneous fMRI and pupillometry showed that pupil dilation tracks task-evoked activity of some subcortical centers including the noradrenergic locus coeruleus, and cholinergic basal forebrain.
@eLife: https://elifesciences.org/articles/23232 pic.twitter.com/9DfjY7oR0Y
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4/11 In my first study with
@ResMaPsychology,@tknapen and@donner_lab we found that the pupil dilates during yes/no deliberations, and that the extent of dilation predicts the upcoming choice especially in subjects with strong prior biases.@PNASnews: https://www.pnas.org/content/111/5/E618 …pic.twitter.com/iHn2Vf5uc8
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"A standardized and reproducible method to measure decision-making in mice"