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Jonathan Pillow
@jpillowtime
Computational neuroscientist @ Princeton. Into brains, math, machine learning. Brain is a computer 4eva.
Princeton, NJpillowlab.princeton.eduJoined September 2010

Jonathan Pillow’s Tweets

Blog post from showing how you can adapt his recently-developed estimator for R^2 to get accurate estimates of representational drift (i.e., that are robust to limited # of trials / response noise)!
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@jpillowtime LAB BLOG POST! We created an estimator of tuning curve similarity (jneurosci.org/content/42/50/). Found another, RDI, in the awesome paper (nature.com/articles/s4146) by @GoardMichael @tylermarks. Compared in simulation, the magnitude of drift could be much larger! 1/3
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Paper is out! A new method to correct for motion induced artifacts in fluorescence intensity time-series traces of calcium imaging. doi.org/10.1371/journa Congrats to . Fun collaboration w/ !
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Do you perform optical imaging in behaving animals? An animal's behavior can introduce motion artifacts into fluorescent time traces. Our new method TMAC works by correcting artifacts *after* spatial alignment (1/4) @jpillowtime @AndrewLeifer @kevinschen13 doi.org/10.1371/journa
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Comparison of different motion correction methods on two-channel optical neural recordings. Each line represents a different animal. A higher score represents more effective artifact removal.
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The paper also introduces the Temporal Relevance Determination (TRD) prior, a prior for temporal receptive fields or spike-history filters, formed from a Gaussian process prior with logarithmically scaled time axis:
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Delighted to have this paper on low-rank receptive field estimation (which we started in 2016) online at last!
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Excited to share some of my pre-grad school work with @jpillowtime, @RudamntaryNeuro and @GregDField . We develop a Bayesian method for estimating space-time separable receptive fields that scales well to high-d settings and correlated stimuli. Code at github.com/pillowlab/VLR-
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Excited to share some of my pre-grad school work with , and . We develop a Bayesian method for estimating space-time separable receptive fields that scales well to high-d settings and correlated stimuli. Code at github.com/pillowlab/VLR-
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Scalable variational inference for low-rank spatio-temporal receptive fields biorxiv.org/cgi/content/sh #biorxiv_neursci
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New work (led by ) introduces "knockout training", a new method for training a DNN in 1-1 correspondence with neurons using (perturbed) behavioral data only!
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Excited to share a new manuscript! Deep nets are great at predicting visual neurons. Yet, they are unable to tell us which artificial neuron directly corresponds to a biological neuron… until now! biorxiv.org/content/10.110 (yes, that is indeed a fictive female fly, good guess!)
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We have just launched our SENSORIUM competition to find the best model of mouse primary visual cortex! 🥳 Have a look at out white paper on #arxiv where we describe the data and the competition tracks in detail: arxiv.org/abs/2206.08666. #NeurIPS2022 Competition track.
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Preprint time! Exciting work on manifestations of system-level pressures on dynamic coding mechanisms at the single-neuron level. Great summary in this thread, and for a visual summary ../2
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Long-time coming preprint led by @vgeadah. We explore why single neurons in the brain may have such diverse and adaptive input-output properties, and how these can emerge from system-level task requirements. What we find is pretty exciting…tinyurl.com/yys4dedb
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Excited to share that I will be joining the Dept of BME at BU! Lab will focus on models of neural circuits in search of theoretical principles of computation and machine learning methods for analyzing neural population dynamics! Keep an eye out for exciting news to come!
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We are delighted to announce that @briandepasquale will be joining @BostonU_BME in January. Brian is a superb addition to @buCSNneuro and @NeurosciBU. Welcome, Brian!
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New paper with analyzing how running affects neural responses in visual areas beyond V1. We found that running increases the reliability of stimulus encoding (even in neurons and areas in which visual responsivity decreases during running)!
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My paper with @jpillowtime analyzing the Allen brain observatory Ca2+ imaging dataset is finally out! rdcu.be/cKaBM #tweetprint to follow
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