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jorient's profile
Jane Orient, MD
Jane Orient, MD
Jane Orient, MD
@jorient

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Jane Orient, MD

@jorient

aka Doctor Aunt Jane, physician in private practice, general internal medicine; executive director, Association of American Physicians and Surgeons

Arizona
aapsonline.org
Joined March 2009

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    1. Jane Orient, MD‏ @jorient 17 Mar 2019
      Replying to @gorskon @Takethatdoctors and

      Science is based on observations. One observation can destroy a beautiful theory. Real scientists try to disprove their theories, not to silence criticism of them.

      17 replies 0 retweets 2 likes
    2. Mark Hoofnagle‏ @MarkHoofnagle 17 Mar 2019
      Replying to @jorient @gorskon and

      Scientific revolutions don’t function by overturning previous theories but by greatly expanding on them. Relativity doesn’t disprove Newton’s laws of motion, it expands on them to high speed and density. If your theory is overturned by a single observation, it was a hypothesis.

      2 replies 1 retweet 17 likes
    3. Mark Hoofnagle‏ @MarkHoofnagle 17 Mar 2019
      Replying to @MarkHoofnagle @jorient and

      More specifically general relativity expanded and generalized Newton’s law of gravitation and special relativity generalized Newton’s laws of motion for high speed. We still use Newton’s theories 99% if the time because we aren’t working at relativistic speeds or in black holes.

      1 reply 0 retweets 13 likes
    4. Mark Hoofnagle‏ @MarkHoofnagle 17 Mar 2019
      Replying to @MarkHoofnagle @jorient and

      While medical reversal is more frequent than that of physics, the previous observations are still true, but may represent outliers, or regress to the mean. Hence the need for replication. Short of fraud, the data remain true, but our understanding of them expands.

      3 replies 1 retweet 9 likes
    5. Mark Hoofnagle‏ @MarkHoofnagle 17 Mar 2019
      Replying to @MarkHoofnagle @jorient and

      Now how in the hell *one observation* would reverse a mature medical theory, which we know are highly dependent on replication, is beyond me and reflects ignorance about how the medical literature functions and appropriate skepticism of new results (as Ioannidis’ emphasizes).

      1 reply 1 retweet 12 likes
    6. Mark Hoofnagle‏ @MarkHoofnagle 17 Mar 2019
      Replying to @MarkHoofnagle @jorient and

      An actual skeptical physician, hearing of a single observation that contradicted a mature finding, replicated, eg for vaccines, in billions of people and thousands of papers, would tell you the far more likely probability is your n=1 observation is garbage.

      2 replies 1 retweet 15 likes
    7. Jane Orient, MD‏ @jorient 18 Mar 2019
      Replying to @MarkHoofnagle @gorskon and

      What if the n = thousands, each and every one dismissed as an anecdote and a coincidence? How about denialism? See brides in the bath case: http://www.jpands.org/vol10no3/miller.pdf …

      2 replies 1 retweet 0 likes
    8. Mark Hoofnagle‏ @MarkHoofnagle 18 Mar 2019
      Replying to @jorient @gorskon and

      Yeah your crank journal is evidence of nothing and the article is frankly conspiratorial. Not interested in the QAnon of medicine.

      4 replies 1 retweet 17 likes
    9. Steven Tiger‏ @SteveTiger999 18 Mar 2019
      Replying to @MarkHoofnagle @jorient and

      Truths from this thread: 1. Education is not an absolute shield against the seductive allure of idiocy. 2. Medical conspiracy-mongers try to sell the notion that current evidence-based consensus should be regarded with suspicion bcuz understanding of science sometimes changes.

      2 replies 0 retweets 11 likes
    10. Mark Hoofnagle‏ @MarkHoofnagle 18 Mar 2019
      Replying to @SteveTiger999 @jorient and

      Yes. Clearly a superior system would declare something true and then *never change* no matter where the evidence goes. If it changed it could be fallible right? We can’t have people believing in fallible beliefs! That’s how you get protestants!

      1 reply 0 retweets 7 likes
      Jane Orient, MD‏ @jorient 18 Mar 2019
      Replying to @MarkHoofnagle @SteveTiger999 and

      You mean like the inquisitorial defenders of the CDC's Holy (and infallible) Vaccine Schedule?

      11:51 AM - 18 Mar 2019
      6 replies 0 retweets 0 likes
        1. New conversation
        2. David Gorski, MD, PhD‏Verified account @gorskon 18 Mar 2019
          Replying to @jorient @MarkHoofnagle and

          Except that the vaccine schedule changes almost every year due to new evidence. You really aren't very good at this, are you?🤦‍♂️

          4 replies 0 retweets 23 likes
        3. someone random‏ @dajerseyboy 18 Mar 2019
          Replying to @gorskon @jorient and

          She's executive director of the AAPS for pete's sake that should be everyone's first, second, and 984th clue

          1 reply 0 retweets 3 likes
        4. Show replies
        1. New conversation
        2. Corazon Fuerte‏ @Corazon17Fuerte 18 Mar 2019
          Replying to @jorient @MarkHoofnagle and

          Time to weigh in. I’m not affiliated with any organization in this thread, just pursuing objective facts that can have context & nuance. Can we all agree vaccines work for immunization AND they can have serious adverse reactions? Here’s one #RealityCheck: https://youtu.be/ERu-CSTQGSI 

          1 reply 1 retweet 1 like
        3. (((Dan Kegel)))‏ @dkegel 18 Mar 2019
          Replying to @Corazon17Fuerte @jorient and

          Everyone in mainstream medicine already agrees that clinical trials and postlicensing vigilance are required to measure vaccine risks, and that vaccines which aren't quite safe should not be on the market. Do you feel a particular serious risk hasn't been measured and is high?

          2 replies 1 retweet 4 likes
        4. Show replies
        1. New conversation
        2. Tony O‏ @tony_oliver 18 Mar 2019
          Replying to @jorient @MarkHoofnagle and

          Control Data Corporation never had anything to do with vaccines. Does the "MD" in your handle (in which you rejoice) stand for "misguided div"?

          1 reply 0 retweets 0 likes
        3. Steven Tiger‏ @SteveTiger999 18 Mar 2019
          Replying to @tony_oliver @jorient and

          psst! Centers for Disease Control...

          1 reply 0 retweets 0 likes
        4. Show replies
        1. Michael Greenhow‏ @mikegreenhow 18 Mar 2019
          Replying to @jorient @MarkHoofnagle and

          pic.twitter.com/hSXGXmopiD

          0 replies 0 retweets 0 likes
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        2. Jane Orient, MD‏ @jorient 18 Mar 2019
          Replying to @AlastairMcA30 @MarkHoofnagle and

          Why do you persist in denying harm to patients? Japan changed to acellular pertussis a decade before US did--how many children got severe permanent brain damage from whole-cell vaccine in that time?

          0 replies 0 retweets 0 likes
        3. Show replies
        1. Bill Dunn‏ @BDSupperClub 18 Mar 2019
          Replying to @jorient @MarkHoofnagle and

          I agree: you’re not good at this.

          0 replies 0 retweets 0 likes
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