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jonatanpallesen's profile
Jonatan Pallesen
Jonatan Pallesen
Jonatan Pallesen
@jonatanpallesen

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Jonatan Pallesen

@jonatanpallesen

Human geneticist, data scientist

Aarhus, Denmark
jsmp.dk
Joined October 2015

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    Jonatan Pallesen‏ @jonatanpallesen 8 Jun 2018

    Genetic correlations with IQ. (Data from Savage et al, 2018)pic.twitter.com/IUQg0R8PiV

    1:58 PM - 8 Jun 2018
    • 221 Retweets
    • 609 Likes
    • Eddie Bear Steven (((Notovitz))) Matthaios Akura_Elvas 😏 Noël Lepère Emmanuel Goldstein Brian Dean Jon Gurutz Arranz Izquierdo Hamstring
    37 replies 221 retweets 609 likes
      1. New conversation
      2. Λlberto Λlbζ Marocchino‏ @albz_marocchino 8 Jun 2018
        Replying to @jonatanpallesen

        Can I get some explanation, how to read the graph? What does it mean correlation? What are the two correlated variables? What correlation formula has been used?

        1 reply 0 retweets 6 likes
      3. Jonatan Pallesen‏ @jonatanpallesen 8 Jun 2018
        Replying to @albz_marocchino

        If there is a positive correlation in the figure, it means that there are genetic variants that influence both the trait on the y-axis and intelligence , and this group of variants in aggregate influence them in the same direction.

        2 replies 1 retweet 8 likes
      4. Picolo Martin‏ @Apestatic 8 Jun 2018
        Replying to @jonatanpallesen @albz_marocchino

        No, it means the same genetic variants that were correlated for IQ correlate with other traits. They have not proven the variants influence anything... not even for height.

        2 replies 0 retweets 4 likes
      5. Jonatan Pallesen‏ @jonatanpallesen 8 Jun 2018
        Replying to @Apestatic @albz_marocchino

        Reverse causation is not possible in genetics. Of course the variants could influence the traits indirectly, though.

        1 reply 0 retweets 2 likes
      6. Picolo Martin‏ @Apestatic 8 Jun 2018
        Replying to @jonatanpallesen @albz_marocchino

        You have no hard evidence that these SNPs are influencing anything. You have no hard evidence they are even functional. These GWAS don't even know for sure what SNP they are correlating... nor to what gene. Saying these SNPs influence anything is outright misrepresentation.

        1 reply 0 retweets 2 likes
      7. Bagel Catcher‏ @wh0sthatd0g 9 Jun 2018
        Replying to @Apestatic @jonatanpallesen @albz_marocchino

        My thoughts exactly. Many of these, like longevity or obesity or even smoking, are also correlated with income levels. Low-income populations typically have worse schools and therefore would score lower on tests. The correlation could be income, not genetics.

        1 reply 0 retweets 1 like
      8. Hamstring‏ @bc_nbc 27 Jun 2018
        Replying to @wh0sthatd0g @jonatanpallesen @albz_marocchino

        Low income, certainly, but improving all schools has resulted in only minor changes in test results, and not all of them were positive changes.

        2 replies 0 retweets 0 likes
      9. Picolo Martin‏ @Apestatic 27 Jun 2018
        Replying to @bc_nbc @wh0sthatd0g and

        Well its getting to the point where it doesn't matter how accurate your statement is. Either they prove genetic cause or they don't, all the correlations in the world won't help if the genes actually don't work or cause said trait or %of trait as stated.

        0 replies 0 retweets 0 likes
      10. End of conversation
      1. New conversation
      2. Charles Murray‏ @charlesmurray 8 Jun 2018
        Replying to @jonatanpallesen @pnin1957

        What's the doi for that, please?

        2 replies 0 retweets 13 likes
      3. Jonatan Pallesen‏ @jonatanpallesen 8 Jun 2018
        Replying to @charlesmurray @pnin1957

        https://doi.org/10.1101/184853  Table in supplementary

        1 reply 1 retweet 20 likes
      4. 1 more reply
      1. New conversation
      2. James Thompson‏Verified account @JamesPsychol 9 Jun 2018
        Replying to @jonatanpallesen @hbdchick

        can you give me the title of the paper please?

        2 replies 0 retweets 0 likes
      3. Jonatan Pallesen‏ @jonatanpallesen 9 Jun 2018
        Replying to @JamesPsychol @hbdchick

        "GWAS meta-analysis (N=279,930) identifies new genes and functional links to intelligence"https://doi.org/10.1101/184853 

        2 replies 2 retweets 11 likes
      4. James Thompson‏Verified account @JamesPsychol 9 Jun 2018
        Replying to @jonatanpallesen @hbdchick

        Thanks very much. Am I right that more papers have come out on this topic in the last two months than in the past 10 years? Seems like that.

        1 reply 0 retweets 6 likes
      5. Tᴏᴍ Vᴀɴ Dʏᴋᴇ‏ @DykeVanTom 9 Jun 2018
        Replying to @JamesPsychol @jonatanpallesen @hbdchick

        IQ is the third rail of sociology

        0 replies 1 retweet 1 like
      6. End of conversation
      1. New conversation
      2. iamreddave‏ @iamreddave 8 Jun 2018
        Replying to @jonatanpallesen @ModeledBehavior

        Great chart. Former smoker and ever smoker. Former means quit and ever includes current?

        1 reply 0 retweets 1 like
      3. Jonatan Pallesen‏ @jonatanpallesen 8 Jun 2018
        Replying to @iamreddave @ModeledBehavior

        Yep

        0 replies 0 retweets 1 like
      4. End of conversation
      1. New conversation
      2. Garry Lee‏ @Gearoidmuar 8 Jun 2018
        Replying to @jonatanpallesen @SteveStuWill

        These aren't "genetic" correlations. They're correlations.

        1 reply 0 retweets 7 likes
      3. Jonatan Pallesen‏ @jonatanpallesen 9 Jun 2018
        Replying to @Gearoidmuar @SteveStuWill

        They are indeed https://en.m.wikipedia.org/wiki/Genetic_correlation …

        1 reply 0 retweets 5 likes
      4. Garry Lee‏ @Gearoidmuar 9 Jun 2018
        Replying to @jonatanpallesen @SteveStuWill

        That's a new meaning of genetic for me!

        1 reply 0 retweets 0 likes
      5. End of conversation

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