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jflier's profile
Jeffrey Flier
Jeffrey Flier
Jeffrey Flier
@jflier

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Jeffrey Flier

@jflier

Harvard University Distinguished Service Professor and Higginson Professor of Physiology and Medicine at Harvard Medical School. Formerly Dean of HMS.

Boston, MA
Joined June 2009

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    Jeffrey Flier‏ @jflier 26 Oct 2019
    • Report Tweet

    Jeffrey Flier Retweeted David Sinclair, PhD AO

    Let’s be clear. Experts on epigenetics I’ve spoken w are extremely skeptical about causal link between epigenetic marks that correlate w chronological age and the aging process, such that aging could be reversed. Look for the scientific literature, not @WSJopinion for answers.https://twitter.com/davidasinclair/status/1187757772957310983 …

    Jeffrey Flier added,

    David Sinclair, PhD AOVerified account @davidasinclair
    Some researchers believe we may be able to slow down—and even turn back—the clock that governs aging in our cells. Here's why that could change pretty much everything. https://www.wsj.com/articles/we-may-not-have-to-age-so-fast-11572012999?mod=searchresults&page=1&pos=1 …
    8:54 AM - 26 Oct 2019
    • 15 Retweets
    • 83 Likes
    • Craig Ski Michael Chapiro ☣️🎨 Sara Villa Egan Renée Stephen Stephen Kearney CommonHealth Vinay Prasad Terry Maratos-Flier
    13 replies 15 retweets 83 likes
      1. New conversation
      2. Paul Summergrad‏ @paulsummergrad 26 Oct 2019
        • Report Tweet
        Replying to @jflier @WSJopinion

        How secure do you think the emerging literature is on the multigenerational inheritance of environmentally mediated events or characteristics ?

        1 reply 0 retweets 1 like
      3. Jeffrey Flier‏ @jflier 26 Oct 2019
        • Report Tweet
        Replying to @paulsummergrad @WSJopinion

        Hard to say- there are so many reports, with widely varying methods and claims. I suspect some of it is right, lots not.

        0 replies 0 retweets 2 likes
      4. End of conversation
      1. New conversation
      2. Michael Joyner‏ @DrMJoyner 26 Oct 2019
        • Report Tweet
        Replying to @jflier @WSJopinion

        So many fountains of youth so little time...... WSJ should not be doing infomercials

        1 reply 2 retweets 10 likes
      3. 1 more reply
      1. halvorz‏ @halvorz 26 Oct 2019
        • Report Tweet
        Replying to @jflier @WSJopinion

        halvorz Retweeted halvorz

        https://twitter.com/halvorz/status/1165786327373295618 …

        halvorz added,

        halvorz @halvorz
        pro tip: if a sentence contains the words 'epigenetics' or 'quantum' you can safely ignore it 95% of the time unless it's in a peer-reviewed article even then it's at least 50% I think
        Show this thread
        0 replies 0 retweets 3 likes
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      1. hypercoagulable‏ @ten0v 26 Oct 2019
        • Report Tweet
        Replying to @jflier @WSJopinion

        Funny that you would make an appeal to authority to arguably the biggest authority in the field. Half the scientific literature you refer to came from his team.

        0 replies 0 retweets 2 likes
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      1. Karsten Suhre‏ @ksuhre 27 Oct 2019
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        Replying to @jflier @minouye271 @WSJopinion

        Agree - age associated methylation marks likely are readouts for gene expression- and as such non causal markers - modifying methylation back to a “younger” state might even do harm, as it reverses what the body might need when it ages.

        0 replies 0 retweets 2 likes
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      1. Adam Ashwal‏ @interwound 27 Oct 2019
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        Replying to @jflier @WSJopinion

        Do you have a recommendation of something to read in this vein? I don't really understand the criticism as you've formulated it. Acetylation, either by programming or entropy, leading to aging phenotypes seems well supported?

        0 replies 0 retweets 1 like
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      1. linhdtu‏ @tuduylinh 26 Oct 2019
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        Replying to @jflier @WSJopinion

        guy is talking his book and has plenty of conflict of interest. One thing i learn from l'affaire WeWork is that being super duper optimistic abt future usually pays off handsomely. One needs to be real lucky to rake off 1B$ like Adam Neumann but otherwise than that it still pays

        0 replies 0 retweets 0 likes
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      1. Prakash Hande‏ @manoorhande 26 Oct 2019
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        Replying to @jflier @WSJopinion

        Obsession is another thing! Most of us are obsessed with our research - we believe that only “our” research will cure disaeases Or other conditions!

        0 replies 0 retweets 0 likes
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