Jesper Svedberg

@jesvedberg

Evolutionary biologist working with fungi, genomics, meiotic drive.

Vrijeme pridruživanja: rujan 2017.

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  1. prije 4 sata

    through the MSUD pathway. This has been a fun project generating some very interesting results, and it's also been a great collaboration between the lab in Uppsala (including @HolkVogan and others) and the Hammond lab in Illinois. (4/4)

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  2. prije 4 sata

    and as a resistance factor. We also show that the gene has been introgressed into N. sitophila, most likely from N. hispaniola. Finally, we show that spore killing can suppressed in certain highly isogenic crosses, and that this suppression is caused by RNA interference, (3/4)

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  3. prije 4 sata

    Using a GWAS approach we identified a single ~2kbp locus that is perfectly associated with the spore killer phenotype. Using various molecular techniques, we confirmed that a single gene at this locus can cause meiotic drive, and that this gene work both as a killer factor (2/4)

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  4. prije 4 sata

    Our new paper on in is now out on bioRxiv. In this thread I will briefly summarize the results. We sequenced genomes from populations of Neurospora sitophila in order to study the Sk-1 "spore killer" meiotic drive element. (1/4)

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  5. proslijedio/la je Tweet
    28. sij

    It is out! Check out our paper, "Building de novo reference genome assemblies of complex eukaryotic microorganisms from single nuclei" in !

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  6. proslijedio/la je Tweet
    20. sij

    I have a PhD position available (3-year funded) to study the evolution of recombination rates using experimental evolution and genomics in fission yeast Application deadline: 16 Feb. For more info see

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  7. proslijedio/la je Tweet
    19. pro 2019.

    A pleasure to work with Nina Wedell and on this paper for a special edition in ProcB on gene drive. I look forward to reading the other contributions

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    9. pro 2019.

    One fly, one genome...and now, one manuscript! The latest from my group on making chromosome-scale assemblies using tiny samples. With fabulous coauthors and

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  9. proslijedio/la je Tweet
    18. stu 2019.

    New preprint, on how *aggregate* recombination modulates: (a) variance in the genetic relatedness of relatives; (b) how rapidly selection purges introgressed DNA. Turns out (a) and (b) are... related! w/ 1/2

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  10. proslijedio/la je Tweet

    Widespread Prion-Based Control of Growth and Differentiation Strategies in Saccharomyces cerevisiae

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    18. stu 2019.

    Our work on a new source of sperm heterogeneity is finally up on biorxiv: Bottom line, we think we've found a set of mammalian genes enabling natural selection between sperm that is far more prominent than we guessed. Tweet summary to follow:

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  12. proslijedio/la je Tweet

    Meiotic drive mechanisms: lessons from Drosophila | Proceedings of the Royal Society B: Biological Sciences

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    28. lis 2019.

    Probably the most unexpected discovery of my career: Massive gene amplification on a newly formed Y chromosome! Great teamwork with my lab!

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    24. lis 2019.

    The two most common causes of hardship in PhD students are an inability to install things on the cluster and choosing popgen for the prestige, rather than out of any real interest in good SNPs.

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  15. proslijedio/la je Tweet
    23. lis 2019.

    New preprint, in which we try to understand Fisher's model of sexual selection. With and David Haig.

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  16. proslijedio/la je Tweet
    21. lis 2019.

    Sometimes the most interesting stories take a while to come together. What happens when you whole genome sequence individual flies from females who can't build synaptonemal complex? Lots of interesting things. 1/n

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  17. proslijedio/la je Tweet
    19. kol 2019.

    Marked Neurospora crassa strains for competition experiments and Bayesian methods for fitness estimates

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  18. proslijedio/la je Tweet
    4. lis 2019.

    Our last Preprint About "haploidizer": The first B-chromosome gene that facilitates female-to-male conversion via genome elimination in # Genome Elimination Mediated by Gene Expression from a Selfish Chromosome

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  19. proslijedio/la je Tweet
    10. ruj 2019.

    We have written a review article about the population genomics of Neurospora, and you can read it here for free:

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  20. proslijedio/la je Tweet
    1. ruj 2019.

    A beautifully written, intelligently dissected, & timely reminder of François Jacob's distinction between day science and night science by Itai Yanai & Martin Lercher. Day science is structured (Popperian); night science is Feyerabendian (anything goes).

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