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jbloom_lab's profile
Bloom Lab
Bloom Lab
Bloom Lab
@jbloom_lab

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Bloom Lab

@jbloom_lab

Lab studying molecular evolution of proteins and viruses. Affiliated with @fredhutch @HHMINEWS @uwgenome.

Seattle, WA
research.fhcrc.org/bloom/en.html
Joined June 2014

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    1. zeynep tufekci‏Verified account @zeynep 27 Sep 2021

      Do people know that the 1890 pandemic was likely caused by another coronavirus, OC43 (that was then novel?) Nowadays, no longer novel, it is one of the causes of the common cold. We're obviously not living in the OC43 pandemic since, and we won't live in a COVID pandemic forever.

      103 replies 542 retweets 2,757 likes
      Show this thread
      Bloom Lab‏ @jbloom_lab 27 Sep 2021
      Replying to @zeynep

      I think evidence for 1889-1890 pandemic being caused by OC43 is pretty dubious. There is good seroarchaeology evidence (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2557748/ …) that there was a flu pandemic (probably H3N8) in 1889-1890. In addition, ... (1/3)

      10:28 AM - 27 Sep 2021
      • 15 Retweets
      • 130 Likes
      • Jonathan Mesiano-Crookston /Denial Is Bad Strategy Michael Oberst #OmikronStoppen J Shepherd och oy ... Anthony J Leonardi, PhD, MS Curwen Ares Rolinson Irene Tosetti Andrew Ewing
      4 replies 15 retweets 130 likes
        1. New conversation
        2. Bloom Lab‏ @jbloom_lab 27 Sep 2021
          Replying to @jbloom_lab @zeynep

          ... after OC43 / 1889-90 idea started to gain popular press, I went back & read some historical accounts of 1889-90 pandemic (eg, https://www.amazon.com/gp/product/1279164530 … & https://www.amazon.com/gp/product/3337889379 …). Drs were already quite familiar with influenza then, and they all thought 1889-90 was flu. (2/3)

          3 replies 5 retweets 56 likes
        3. Bloom Lab‏ @jbloom_lab 27 Sep 2021
          Replying to @jbloom_lab @zeynep

          As far as I can tell, argument for 1889-90 being OC43 comes from one study that briefly does a molecular clock analysis that put divergence of OC43 and BCoV in late 1800s, and then popular media ran with it without much examination. (3/3)

          6 replies 8 retweets 69 likes
        4. Show replies
        1. Alice‏ @Cererean 27 Sep 2021
          Replying to @jbloom_lab @zeynep

          there's a flu pandemic pretty much every year though

          0 replies 0 retweets 1 like
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        1. New conversation
        2. Karl Pettersson‏ @KarlPettersso10 27 Sep 2021
          Replying to @jbloom_lab @zeynep

          Karl Pettersson Retweeted Karl Pettersson

          Or two pandemics within a decade (mortality was elevated several years after 1889)?https://twitter.com/KarlPettersso10/status/1442535895870197762 …

          Karl Pettersson added,

          Karl Pettersson @KarlPettersso10
          Replying to @KarlPettersso10 @zeynep and 2 others
          But maybe there was both a flu and a corona pandemic within a decade (gien the frequency of pandemics during 20th Century, that may not be too far-fetched). This "two-pandemic hypotehsis" might also explain the seemingly long duration of the pandemic period starting 1889.
          1 reply 2 retweets 8 likes
        3. Jiří Hudeček‏ @HuJirui 27 Sep 2021
          Replying to @KarlPettersso10 @jbloom_lab @zeynep

          Jiří Hudeček Retweeted Jiří Hudeček

          In Austria and Bohemia, 1888 saw similar mortality as 1890.https://twitter.com/HuJirui/status/1434508655672668172?s=20 …

          Jiří Hudeček added,

          Jiří Hudeček @HuJirui
          Zvýšení úmrtnosti je ale vidět na skupině 60+, a bylo dlouhodobé až do konce pandemie v roce 1893. První vlna na začátku roku 1890 sice vedla k mimořádně smrtelnému jednomu měsíci i v celkové mortalitě, ale jinak byly další vlny podobné "zlé" chřipkové sezoně v roce 1888. 2/2 pic.twitter.com/2jQ4pm5tRe
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          0 replies 1 retweet 3 likes
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