Journal of Biological Chemistry

@jbiolchem

The Journal of Biological Chemistry is a publication of the . Publishing research motivated by biology, enabled by chemistry. EiC:

Rockville, Md.
Vrijeme pridruživanja: ožujak 2012.

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  2. JBC Editorial Board Member Dr. Jeanne Hardy of is Chair of the "Pharmaceutical Biophysics" symposium and has put together a great lineup of speakers. Be sure to catch the talks at and her recent work published in JBC (below).

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    A reactive lipid compound produced during oxidative stress contributes to HDL dysfunction and .

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  4. Wu et al. show that knocking down USP3 slows cell growth and shrinks tumors in mouse models of breast cancer, identifying USP3 as a promising therapeutic target for treatment of breast cancer.

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  5. Here, Bartel et al. demonstrate how the drug archazolid selectively kills cancer cells based on the enyzmatic activity of the cellular energy sensor AMPK.

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    I also wrote an article with on the characteristics, development, treatment, and current research of cancers for ! It's written to be easy to read for non-scientists and is available here:

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  7. are needed for cell division and are a target for therapies. Niu et al. report that a new drug, tirbanibulin, binds tubulin reversibly and may show lower toxicity than available tubulin-binding drugs.

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  9. On this , we'll be sharing cancer-related research covering the mechanisms underpinning cancer and that explore promising therapeutic strategies. Ong and Torres provide an excellent overview of cell division in this JBC award article.

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  10. Paper in Press: "Estrogen-induced FOS like 1 regulates matrix metalloproteinase expression and the motility of human endometrial/decidual stromal cells" -

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  11. Janiszewska et al. summarize recent findings and new therapies targeting cell adhesion molecules in cancer. Paper in Press: "Cell adhesion in cancer: Beyond the migration of single cells" -

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    An impressive collection of interesting reviews!

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    2015 paper showing how a Chinese bat recombined with a SARS-CoV can use ACE2 to efficiently enter human airway cells and replicate, suggesting “a potential risk of SARS-CoV re-emergence from viruses currently circulating in bat populations.”

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  16. The 2019 compendium of JBC Reviews highlights findings from established and emerging fields in biological chemistry. JBC Reviews are written by invited experts and can be downloaded for free on the JBC website. Enjoy!

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    Inside : Researchers at and colleagues report a new mechanism for detecting foreign material during early immune responses.

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  18. Paper in Press: "Leukocyte-associated immunoglobulin-like receptor-1 inhibits T-cell signaling by decreasing protein phosphorylation in the T-cell signaling pathway"

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  19. Paper in Press: "Sirtuin 1 reduces hyaluronan synthase 2 expression by inhibiting nuclear translocation of NF-kB and expression of the long-non coding RNA HAS2-AS1" -

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    and I have written a perspective on a great paper by John Denu on SIRT6 activators in this week's issue of .

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