Jason Bobe

@jasonbobe

Making extraordinary biotechnologies useful for everyday life.

NYC Boston SF
jasonbobe.net/about.html
Joined March 2007
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  1. Retweeted
    30 Jul 2020

    LymeMIND's connected with to discuss the Resilience Project, which seeks to discover why some people may be resistant or immune to . Check it out - link in bio!

    2 retweets 8 likes
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  2. Retweeted
    3 Jul 2020

    (1/n) Excited to share Handyfuge-LAMP; a low-cost & electricity-free centrifugation for isothermal SARS-CoV-2 detection in saliva. With COVID19 cases increasing globally, diagnostics needs to be accessible to everyone - including resource limited regions

    92 replies 1,977 retweets 5,020 likes
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  3. 30 Jun 2020

    w/ , we wrote a forum commentary unpacking key take-home messages for researchers that seek to both advance scientific discovery & explore alternative models of governance that engage, respect, & honor the civil rights of volunteers. /end

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  4. 30 Jun 2020

    So, back to this PDF. We are fortunate that legal scholars, Barbara Evans and Susan Wolf, devoted an entire legal review to assess its legal standing. TLDR; questionable, at best. But, that hasn't stopped the chilling effect it has had on researchers. 6/n

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  5. 30 Jun 2020

    Volunteers may also lead their own research. People like (RIP ) Hugh Reinhoff Jr. () & others, have shown many possibilities for direct action in advancing discovery. 5/n

    1 reply 3 likes
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  6. 30 Jun 2020

    Or research volunteers might aggregate their personal research data and donate it to causes or orgs they care about. Rare diseases and understudied health conditions lose valuable time & capacity to discover by having their longitudinal data sitting in disparate silos. 4/n

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  7. 30 Jun 2020

    Or to ensure their privacy through the inspection of data being held about them by others, potentially aided by a trusted third party. Imagine if you didn't have access to your own financial records, and the IRS assigned you an accountant for filing your taxes. 3/n

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  8. 30 Jun 2020

    There are many good reasons why research volunteers may want access to data generated about them through their participation in studies and trials, including a desire to be more informed about nature of research they are involved in 2/n

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  9. 30 Jun 2020

    It's long past time to get rid of policies that block researchers' efforts to engage, respect, & honor the civil rights of research volunteers. A rather egregious example is a PDF that appeared on website in '14 & I explain 1/n

    1 reply 1 retweet 3 likes
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  10. Retweeted
    26 Jun 2020

    The Lyme rash (erythema migrans) on skin of color is difficult to find in dermatological references and I'm asked often to provide some, so I was delighted to receive this (I'm assured the young man pictured made a full recovery).

    13 replies 270 retweets 748 likes
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  11. Retweeted
    27 Jun 2020

    How to use gene editing to fight heart disease, the #1 killer worldwide: A thread 10+ years in the making. This one starts in 2009 when I was a postdoc in lab / studying ❤ risk factors like cholesterol & triglycerides. (thread)

    20 replies 261 retweets 805 likes
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  12. Retweeted
    4 Jun 2020

    🚨I wrote about COVID-19 long-haulers—the thousands of people who’ve been struggling with *months* of debilitating symptoms. Many have faced disbelief from friends and medical professionals because they don’t fit the typical profile of the disease. 1/

    249 replies 4,203 retweets 6,695 likes
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  13. 11 May 2020

    Animal model data from a new prototype vaccine for Lyme Disease. A ferritin nanoparticle fused with OspA molecules from seven strains of Borrelia including B burgdorferi, B afzelii, B bavariensis and several B garinii.

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  14. Retweeted
    10 May 2020

    Lyme advocacy has the unique and incredible history of being driven forward by mothers who KNEW that something was happening to their children. Keep fighting for good science and for progress mamas!

    Happy Mother’s Day! Thank you to the women who helped discover Lyme & who are leading the way💚
    1 reply 10 retweets 36 likes
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  15. Retweeted
    9 May 2020

    From Rino Rappuoli et al "Over 1100 memory B cells were single cell sorted using the stabilized prefusion form of the spike protein and incubated for two weeks to allow natural production of antibodies."

    4 replies 21 retweets 42 likes
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  16. 6 May 2020

    For covid-19 patients anywhere in the country

    The Precision Recovery platform developed at serves as a tracking & system for patients:
    1 retweet 3 likes
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  17. 2 May 2020

    sous vide foodies rejoice (and unite)

    RT-LAMP test for from Brian Rabe and Connie Cepko: 30 min, requires a 65 °C bath (does not require a PCR machine or other specialized equipment), can detect 1 viral RNA copy per µL, works on saliva, readout is color change.
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  18. Retweeted
    1 May 2020

    Even as a virologist, there’s one insidious type of bacteria that weighs on my mind. Borrelia- carried by ticks, causes Lyme disease. Thank you for recognizing that we do after all need a vaccine (GSK pulled theirs due to unsubstantiated fears).

    17 replies 76 retweets 247 likes
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  19. Retweeted
    19 Apr 2020

    I’m a virologist, biotech investor (vaccines, drugs, & diagnostics). For ease, here are all my explainers in one place (why is SARS2 worse than SARS1? What are antibodies? Is vaccine possible?), full of analogies even kids will understand. Will help you know what’s true.

    112 replies 1,523 retweets 3,345 likes
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  20. Retweeted
    12 Apr 2020

    The NIH is looking for healthy volunteers to test the prevalence of COVID in asymptomatic Americans. They will ship you an at-home blood test that you mail back, and will return your results to you.

    10 replies 429 retweets 561 likes
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