james lynch

@jameslynch4evr

project leader ICPHAM (a long term early experiment) - born 1962, i believe the answer for aging is in the experiments of today, soccer player, photo taken 2019

Virginia, USA
Vrijeme pridruživanja: listopad 2018.

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  1. proslijedio/la je Tweet
    9. pro 2019.

    Feeling honored that our paper describing the undulations of the aging plasma proteome has been so well received. I’ll summarize the main findings in this thread!

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  2. 13. stu 2019.

    thank you to all for this impressive information - we are one step closer to solving the aging puzzle

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  3. 24. ruj 2019.

    due to the significant risks involved, disclosure via social media has been decided against, but half of the current followers have received contact info & 100% of requests for more info have been granted

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  4. 24. ruj 2019.

    not wanting it to be overlooked, ICPHAM is conducting a long term exploratory experiment on one test subject (begun 1999 to 2019 so far, dosages every 4 hours) no clear positive or negative result has been demonstrated so far

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  5. 24. ruj 2019.

    in present day, it is mentioned in Endocrinology texts but is given little attention (with a little effort, experts should be able to identify it)

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  6. 24. ruj 2019.

    so this cell to cell communicator was assumed to be of little importance despite the fact that it is present in large quantities in young adult humans (it declines with age)

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  7. 24. ruj 2019.

    most of the scientific community of a quarter century ago concluded that no benefit in mice = probably no benefit in humans

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  8. 24. ruj 2019.

    this results in no benefit in mice. experiments performed in mice have demonstrated disappointing negative results

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  9. 24. ruj 2019.

    evidence suggests that mice, having evolved without this cell to cell communicator, have evolved without the receptors as well

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  10. 24. ruj 2019.

    ICPHAM = Investigating Cell to cell communicators Present in Humans but Absent in Mice

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  11. 1. ruj 2019.

    thanks for passing on this important info

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  12. 20. kol 2019.

    : Longitudinal effects of aging on plasma proteins levels in older adults – associations with kidney ...

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  13. 15. kol 2019.

    thank you for this impressive work. one of the greatest challenges remains the lack of universally agreed biomarkers. while this biomarker is non modifiable, it may prove to be useful.

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  14. 15. kol 2019.

    the "best guess" of this investigator is that the cell to cell communicator may impact longevity, but has little to no impact on neural functions

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  15. 15. kol 2019.

    since the cell to cell communicator is present in humans, but absent in mice, areas in which the 2 species differ may be impacted

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  16. 15. kol 2019.

    while an early exploratory experiment is suggestive, the mechanism of it's action remains unknown

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  17. 15. kol 2019.

    experiments with mice have demonstrated no benefit, but experiments with humans remain inconclusive

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  18. 15. kol 2019.

    evidence suggests that mice, having evolved without this cell to cell communicator, have evolved without the required receptors as well

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  19. 15. kol 2019.

    after a quarter century of working on this project, i have found only one cell to cell communicator that matches this criteria

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  20. 15. kol 2019.

    ICPHAM project = Investigating Cell to cell communicators Present in Humans but Absent in Mice

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