Michael Cuccarese

@i_draw_hexagons

biologist with a chemistry love affair. recursion pharmaceuticals. opinions mine. Please tell me stories about how ochem was your least favorite class.

Salt Lake City, UT
Vrijeme pridruživanja: svibanj 2015.

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  1. proslijedio/la je Tweet
    11. sij

    New screen identifies small molecule inhibitors that improve immunotherapy via a myeloid-cell targeted nanoformulation. ?

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  2. proslijedio/la je Tweet
    9. sij

    You still using M1/M2??? I recommend looking at scRNA-seq data by former Kevin King and colleagues: 5 neutrophil and 6 macrophage subsets in acute MI, IFN stimulation begins in bone marrow♥️🦴

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  3. proslijedio/la je Tweet
    23. pro 2019.

    Excited to announce our first spin-out company to be led by biopharma industry veteran Dr. Mani Mohindru! Building our machine to industrialize drug discovery and now building companies to take the drugs we find to patients with exquisite focus. The Recursion team is strong💪

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  4. Here's a nice overview of the state of utilizing AI in drug discovery - underscores some of our key priorities in data quality and reproducibility at

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  5. proslijedio/la je Tweet
    29. stu 2019.

    SPOTLIGHT: VEGF-A drives TOX-dependent T cell exhaustion in anti-PD-1-resistant microsatellite stable colorectal cancers. Originally published in . Read our full digest =>

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  6. 7. stu 2019.

    Awesome commentaries (loaded with some fantastic culinary analogies I might add) on the tech/lifesci VC perspectives in drug discovery.

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  7. No matter how much I am exposed to them, 2 things will never cease to amaze me. 1) The unbelievable views in southern Utah and 2) the ability to remote in from here to crunch data.

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  8. proslijedio/la je Tweet
    7. lis 2019.

    Last week was big for and with and entering into a multiyear collaboration. Learn more on what this means for the future of the industry from our CEO and co-founder .

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  9. proslijedio/la je Tweet
    20. ruj 2019.

    Major debate. You arrive home late and you are "so hungry" You open the fridge and see pizza. Do you:

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  10. proslijedio/la je Tweet

    Have you ever wanted to make really, really questionable food from recipes generated by a still-learning AI? No? Well I made this anyways.

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  11. proslijedio/la je Tweet

    Gratifying to see such a vigorous, compelling medical community response to Goldfarb's here & social media. Aligned w/ some points from August essay "Meeting the challenges of modern medicine will require more than seeing patients."

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  13. Local generation of otherwise systemically toxic cytokines is the IO holy grail in my opinion. Beautiful work:

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  14. proslijedio/la je Tweet
    18. kol 2019.

    AbbVie gets its FDA OK for inhibitor , but don’t look for this one to hit execs’ lofty expectations

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  15. Awesome write-up of why we do what we do at Recursion

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  16. proslijedio/la je Tweet

    🇬🇧Pop. 65 million 🇺🇸Pop. 330 million (5x) 🇬🇧Video game revenues: ≈$5 billion 🇺🇸Video game revenues: ≈$25 billion (5x) 🇬🇧Gun homicides (2017): 31 🇺🇸Gun homicides (2017): 14,542 (469x) Stop blaming the video games you absolute morons.

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  17. proslijedio/la je Tweet

    This tweet will, sadly, always be relevant.

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  18. 2. kol 2019.

    is on spotify. Truly doesn't matter how the rest of this day goes.

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  19. proslijedio/la je Tweet
    30. srp 2019.
    Odgovor korisnicima

    Yes. The part that we oncologists hang our hats on is the persistent separation after curves flatten. I don’t use these PD1 drugs myself (prostate), but hear my (lung) colleagues council patients: “most people get zero benefit from this drug. A few are cured.”

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