New work from us - Systems Immunology of #MECFS and the targeting of the vagus nerve and inflammatory reflex - an RCT of INMEST showing (~30%) symptom relief biorxiv.org/content/10.110
Conversation
1/ Petter hey! Excellent paper and huge congrats to your entire team! You know I follow your work closely and these new findings on #ME/CFS are truly interesting. Thanks for citing my work on possible #pathogen-driven + gut-brain #microbiome axis dysregulation in the disease
2/ On page 8 you mention that gut microbiome dysbiosis is likely in ME/CFS which might dysregulate vagus signaling, and also that persistent EBV can induce IL-17. Under such conditions, the chronic immune activation you noted in ME could result from the immune system’s…
1
6
28
3/…attempt to keep persistent intracellular pathogens like EBV in the blood/CNS “in check” and/or the immune system’s attempt to continually mitigate increased pathobiont virulence in an increasingly dysbiotic gut microbiome environment.
1
3
26
Show replies

