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This is the real deal ! It not only demonstrates that adenosine recovery by cells is inadequate, and gets metabolised to depletion, but purine signalling throughout the body AND the brain are going through issues. Adenosine and normal sleep are intertwined.
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If I search for this, I find papers that say trypanosomes salvage purines from their host. That might explain the reported similarity between sleeping sickness and this illness.
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