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#Mortality#Senolysis Here is a promising pathway to kill old cells, while sparing healthy cells.... http://fb.me/8z5jYcMQX -
Aging and
#rheumatic diseases: need of targeting senescent cells and of a therapeutic killing of senescent cells using small molecules#senolytics#senolysis#GISEA -
ICYMI | In this News&Views, Katharina Wolter & Lars Zender explore how cancer therapies can trigger
#senescence of tumour cells and a new study showing that eradication of therapy-induced senescent cells (#senolysis) can improve#LiverCancer therapy https://go.nature.com/30Vhzq3 pic.twitter.com/HzZtnnPIpw
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Is
#senolysis—removing senescent cells—an opportunity to prevent/reverse type 2#diabetes? In mice, removing senescent β-cells improves glucose#metabolism & function of remaining β-cells; also seen w/ human cells https://doi.org/10.1016/j.cmet.2019.05.006 …#MetabolicSyndrome#agingpic.twitter.com/jGD168gxSV
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がんを老化させて、老化細胞を叩き、がんを殺す手法ね。 結局がん種とステージによる。有効なセグメントをどう規定するかが重要だわな。ところで、がん幹細胞はどうなった?
#senolysis#cancerhttps://www.nature.com/articles/s41586-019-1607-3 … -
Inhibition of CDC7 and mTOR enables selective apoptosis of liver cancer cells with TP53 mutations |
#livercancer#senolysis#CDC7#TP53#sertraline#mTOR | René Bernards & Leila Akkari@oncodeinstitute@NKI_nl@LeilaAkkari1@BenteBenedict | Nature@nature https://rdcu.be/bSMKD pic.twitter.com/Hv2rARWLau
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Clearance of senescent islet cells improves glucose metabolism and β cell function http://bit.ly/2XwlvdK
#NBThighlight#Senolysis
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