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  1. Apr 5

    Whoa—New study found active in the intestines of children for up to 36 days—70% of infected children carried the active virus without showing any symptoms, giving worry to “invisible transmitters”. Of 22 cases, 20 were children under age of 6. 🧵

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  2. Apr 9

    📍ITALY 🇮🇹 SCHOOL REOPENING: Nationwide in Italy, 15-20 days after schools reopened, surged. The “rate of growth of daily cases in all Italian regions provides some evidence in favor of a link between school reopening and resurgence”. Detailed 🧵 by

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  4. 1/ Who wants to tell the Times that the rates of infections worldwide, in the US, and in US prisons are likely ~the same, and any differences in reported rates probably result solely from the testing of asymptomatic prisoners?

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  5. is not past tense. It’s something that will keep happening if is allowed to circulate almost freely among younger unvaccinated age groups. I still can’t believe how this fact is totally ignored when briefing the public about next steps in pandemic response.

  6. Apr 6

    33 participants who received both doses of the Moderna mRNA-1273 vaccine had blood drawn over 6 months after vaccination. neutralizing activity was maintained in all the patients. A half-life of 202 days was determined for the live-virus neutralization activity.

  7. Reinfection may be more common than recorded & 2nd time may be worse. Frm Brazil: "The 2nd episode was assoc'ed w/different strains, higher viral loads & clinical symps..persons w/mild COVID-19 may [not] have detectable humoral immunity"

  8. Apr 8

    Six patients previously infected with the original virus received the BNT162b2 vaccine. Before vaccination, they had neutralizing activity against the B.1.1.7 and P.1 variants but not B.1.351. After one dose, neutralizing activity against all variants increased greatly.

  9. Apr 3

    Epidemiologist Dr. , who led smallpox global eradication, expressed concerns over new variants and stressed need for a plan in addition to vaccines. “I’m quite worried—We seem to be getting variants of concern almost every week”.🧵

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  10. Apr 7

    Convalescent serum from persons who had recovered from infection with 501Y.V2, a variant in South Africa, showed potent neutralization of pseudoviruses expressing spike proteins of the original variant (D614G), the 501Y.V2 variant, and the P.1 variant in Brazil.

  11. 20 hours ago

    Pfizer unveils the first orally administered inhibitor of the main protease to enter clinical trials. Inhibiting this protease will prevent the virus from cleaving parts it needs to reproduce itself.

  12. Apr 7

    2/ In fact, I would go even further and make the companies conduct more preclinical work before allowing them to conduct clinical trials in children. is a cold for almost any healthy child; the bar for experimental therapies should be exceptionally high.

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  13. A new X-ray crystallography screen of more than 5,000 drug compounds has found seven that bind to ’s main protease and show target-specific antiviral activity. Of these, two show potential as candidates for preclinical testing.

  14. 13 hours ago

    An alarming study from Israel shows the prevalence of the South African strain among vaccinated individuals eight times higher than its prevalence in the unvaccinated.

  15. Apr 8

    Icahn School of Medicine NYC group: "Our data suggest that lower neutralising antibody titres might be problematic in the context of newly emerging variants, considering that this approach could leave some vaccinees unprotected." Oh dear...

  16. Apr 7

    Over 50% of people in the have antibodies to (14 March 2021). Many more can be expected to have immunity. When will the pandemic be considered over?

  17. Apr 5

    📍 New CDC guidance now admits fomite (surface) transmission of is very rare and low. Glad science is updating. This also means droplets and aerosols (Microdroplets) are the the main culprits.

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  18. Apr 8

    Those who have recovered from have antibodies to the spike protein. In 43 such persons who received a first mRNA vaccine dose, high levels of neutralizing antispike antibodies were produced — even higher than after a second dose in 67 other cases.

  19. Apr 6

    Analysis of serum samples from patients convalescing after infection and after vaccination with BBIBP-CorV or CoronaVac vaccines in China showed neutralizing-antibody titers against the B.1.1.7 strain that were similar to those against the wild-type strain.

  20. Apr 5

    In the Covid-19 Vaccine Resource Center, provides concise and engaging answers to clinicians’ questions about Covid-19 vaccination and to the questions and concerns patients will raise.

  21. The third story in the this morning on how some Americans actively seek to make the pandemic worse. First the ruling on prayer groups, then on in prisons, and then purveyor of lies, misinformation on .

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