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Mapping human cell phenotypes to genotypes with single-cell genomics. Fig. Genetic manipulation toolkit to link phenotype to genotype by using stem cells Ref: http://bit.ly/2vEcsiF
#singlecell#scRNAseq#phenotype#genotype#genomicspic.twitter.com/E4GdJ8Qd1N
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We developed a database in which we extracted the results of attempted treatments for rare metabolic diseases from over 1000 scientific papers, formalized the results using
#phenotype#ontologies and#LinkedData and make all data available through#SPARQLhttps://www.biorxiv.org/content/10.1101/2020.01.08.897223v1 … -
Beautiful explanation from Les Biesecker of the significance of
#phenotype in enabling sensible clinical reporting from genome data. https://genomemedicine.biomedcentral.com/articles/10.1186/s13073-019-0696-9 … -
Happy
#floralfriday! These grapefruit blossoms are from one of our precocious bloomers. It blooms like crazy and makes the greenhouse smell great!#citrus#phenotype pic.twitter.com/LyhVl0KUdK
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Check out this #TransposableElement#phenotype in#maize: Multiple#copia#retrotransposons in the promotor of the newly mapped stiff1 gene repress its transcription.
more lingnin and cellulose in cell walls
stronger maize stalks
http://www.plantcell.org/content/early/2019/11/04/tpc.19.00486 …pic.twitter.com/IzPDtLiMJI
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Great news for ash dieback
#resistance breeding!#Genomic estimated breeding values derived from top SNPs can predict disease#phenotype with 90% accuracy. Excellent how#Genomics#BigData can be used for#forest health!https://twitter.com/KewScience/status/1196460781837193218 … -
Allison will do anything to save her son Ben’s life. As a scientist and pioneer in her field, she is used to pushing the boundaries in her quest to understand the universe.
#newrelease#bookboost#amreading#amwriting#phenotype http://ow.ly/eKnb50xoKV4 pic.twitter.com/Xbu9tlELTx
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Ben knows he is different. What makes Ben different may be what saves them all. What makes Ben different may change the natural order of humanity.
#newrelease#bookboost#amreading#amwriting#phenotype http://ow.ly/eKnb50xoKV4 pic.twitter.com/Hr8lMMY1Am
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We conclude an exciting month of
#OHDSISocialShowcase work with this from Youjin Park et al: “ICARUS WINGS” … new phenotyping of asthmatics using long-term followed measurement data.#TrajectoryClustering#Phenotype#RWE#JoinTheJourney
https://www.ohdsi.org/2019-us-symposium-showcase-102/ …pic.twitter.com/uO38EoB4uO
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This
#OHDSISocialShowcase work comes from Karthik Natarajan and@ColumbiaDBMI collaborators: "A Collaborative Approach to#Phenotype Development: Framing Conceptset Discovery as a#MachineLearning Problem.”#Collaboration#JoinTheJourney
https://www.ohdsi.org/2019-us-symposium-showcase-53/ …pic.twitter.com/8V8mrgTTS9
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Congrats to assistant professor Karthik Natarajan and the Columbia DBMI Phenotype Workgroup, as their research for the 2019
#OHDSI Symposium was featured today in the#OHDSISocialShowcase! Check out all the collaborators!#Phenotype#Cohort#MachineLearning#JoinTheJourneyhttps://twitter.com/OHDSI/status/1222884400641298435 …
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You would need phenoytpic data to see if these changes have any biological relevance - please no dN/dS blackbox stuff either... Stick a dinucleotide change into these things and there's your selected site - right there!
#Phenotype -
New paper on
#genome and#phenotype data of 2570 healthy elderly@NatureComms@UNSWMedicine link to read: https://go.nature.com/38R62eh#CPHCE#Healthcare -
Aujourd'hui, nouveau jour, nouvelle rubrique, nouvelle définition !
Qu'est-ce-que les gens de couleur
?? Ce sont des non esclaves, soient affranchis ou nés libres, de couleur de peau foncée.
#definition#free#slavery#lkdef#phenotype pic.twitter.com/86iqQhg0rL -
The software package polygene enables easy and convenient allelic
#Phenotype‐ or#Genotype‐based analysis for both autopolyploids and diploids. Read the full#OpenAccess Methods in#Ecology and#Evolution article here: http://bit.ly/2RUlP58 pic.twitter.com/cjuZNJq6hb
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Integrating
#WholeGenomeSequencing w/#metabolomics & medical#imaging ↑ early detection of#aging-related diseases Health Nucleus identified#genetic disorders via#genotype#phenotype association https://doi.org/10.1073/pnas.1909378117 …#genomics#metabolites#biomarkers#sequencingpic.twitter.com/P2IVVpl0LC
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The
#Sjögren Big Data Consortium is an international, multicentre registry based on worldwide data-sharing cooperative merging of pre-existing databases from leading centres in clinical research in Sjögren’s syndrome from the five continents
#phenotype#diagnosis#ESSDAIhttps://twitter.com/SjogrenEurope/status/1220458301021966337 … -
We participated in the
#Sciencenight at Franklin K-8 School in#Corvallis#CSD509j@CSDNow & interacted with budding scientists learning about#DNA#genome#mutations#genes#phenotype seed identification & counting#MachineLearning &#AI#STEM@Planteome supported by@NSF_BIO https://twitter.com/GrameneDatabase/status/1220794079987941377 …pic.twitter.com/MdDjTwleaR
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Great to be part of the
#Sciencenight at Franklin K-8 School in#Corvallis#CSD509j@CSDNow@SuptNoss Kids learned about#DNA#genome#mutations#genes#phenotype#MachineLearning and#AI Contributions from@GrameneDatabase@Planteome supported by@NSF_BIO@CGRBOregonStatepic.twitter.com/4piPx6JQfM
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@IngoHelbig and the@ChildrensPhila#ENGIN team are exploring the genetic determinants of#pediatric#epilepsy. Highlights the need for discrete#EHR#phenotype to describe presentation, diagnosis, best treatments, and expected trajectory. https://www.ncbi.nlm.nih.gov/m/pubmed/28566552/ …pic.twitter.com/VVudbIHj9z
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