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Our paper with
@ChandaLab06 on hHCN1#ionchannel activation is under review, you can check it out at sneak peek: https://bit.ly/35OJV7A Been a great adventure to validate Anton simulations and show that S4 helix break is critical for hyperpolarization activation!

1/4pic.twitter.com/NnT234aKZRPrikaži ovu nit -
The Dixon Lab
@UCDavis is seeking to recruit a post-doctoral scientist to join our team. If cardiovascular physiology is your jam or you want to work on how aging affects calcium#IonChannel function, regulation, & trafficking, DM me! https://app.joinhandshake.com/jobs/2728180/share_preview … -
Excited to share we did a BIG screen and found a new
#ionchannel! TMEM206 forms chloride channels that are activated by acidic pH. They are expressed in all vertebrate cells, physiological role pending. Check out our preprint at@biorxivpreprint https://www.biorxiv.org/content/10.1101/667600v1 … (1/3)Prikaži ovu nit -
A postdoc position will soon be available in my lab
@UniofOxford Looking for an electrophysiologist to work on exciting new project about regulation of ion channels by engineered single domain VHH antibodies. More details to follow, or contact me#ionchannel#postdocPrikaži ovu nit -
I am proud to share the latest research from the lab (https://doi.org/10.1016/j.bbamcr.2018.06.013 …) on dynamic trafficking of the
#ionchannel Cav1.2 pic.twitter.com/FoBz3ghrvY -
Meeting my rockstar! Francisco "Pancho" Bezanilla, ledgendary science hero with a lifelong dedication on science from
#squid to#ionChannel, Especially the voltage-gated ones! So happy! pic.twitter.com/Zswm0nVPas
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Three new papers describing the
#cryoem structures of TRPML1#ionchannel today in@nature, including one at 2.9 Å!
http://www.nature.com/nature/journal/vaop/ncurrent/full/nature24055.html …pic.twitter.com/do8txtVRqN
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The sodium leak channel NALCN is one of the least known members of the 24-TM
#ionchannel family - and our work shows it is modulated by both voltage and extracellular calcium: https://www.biorxiv.org/content/10.1101/740456v1 … 1/3pic.twitter.com/W9A2j4XOM6
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Check out our new paper on Calmodulin promiscuous binding to
#ionchannel in@PLOSCompBiol. We analyzed MD simulations using pretty neat data analysis tools. Congrats Annie Westerlund, first author! http://journals.plos.org/ploscompbiol/article?id=10.1371/journal.pcbi.1006072 …pic.twitter.com/BBMmV8orHp
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He said it’s “his last tour” (before retiring). Let’s embrace “the weird ion”, F- by Prof. Chris Miller. Always an honor to listen to his talks!
#fluoride#ionchannel pic.twitter.com/Z8NK3Xrffv
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Interested in any aspect of ion channels and membrane transport, from structure to disease? Want to do a PhD
@UniofOxford? Applications for the@wellcometrust 4yr OXION PhD programme now open. Fully funded studentships available! https://www.medsci.ox.ac.uk/study/graduateschool/courses/dtc-structured-research-degrees/ion-channels-and-membrane-transport-in-health-and-disease-oxion …#ionchannel -
Celebrating my lab’s brand spanking new, fundable R01 score today with an aptly named beer. Gotta love those
#calcium#ionchannel super clusters! pic.twitter.com/BOtu3szLxS
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Our collaborative paper with
@moiseenkovabell is out, uncovering how PIP2 activates and CaM inactivated the TRPV5#ionchannel https://www.nature.com/articles/s41467-018-06753-6 …@aytoryaz -
The Brazilian wandering
#spider Phoneutria nigriventer introduced me to the fantastic world of#venomresearch#WomenInSTEM Its#venoms contains the remarkable#toxin Phα1β, a potent#IonChannel inhibitor#ToxinTuesday#chronicpain#Drugdiscovery@VenomsLab@IMBatUQpic.twitter.com/LW5JSmuEzK
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Hey
#IonChannel community! Ever wonder why your favorite channel likes to form clusters in the PM? Check out our most recent collaborative work with@lfsantana68 for some answers. A stochastic model of ion channel cluster formation in the plasma membrane http://jgp.rupress.org/content/early/2019/07/31/jgp.201912327 … -
In Feb 2018 when two new partner papers in
@nature by Yang, Cui et al. found that "ketamine quickly elevates mood by blocking NMDAR-dependent bursting activity of LHb neurons" the inner#IonChannel nerd in me was glued to the screen. The future is bright. https://twitter.com/nytimes/status/1095525517527318529 …Prikaži ovu nit -
New collaborative work
@JPhysiol describing the mode of which pannexin-1 is activated or inhibited is permeant-selective#pannexin#ionchannel https://www.ncbi.nlm.nih.gov/pubmed/31698505 -
Update to my animal “channelopathies” lecture. “Fainting goat syndrome” now available in Spaniel flavour (though I am not sure anyone has checked if the mutation is the same chloride
#ionchannel P.s., don’t worry, he’ll be fine :-) pic.twitter.com/hGKpkuESth
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A chicken nugget receptor?
@strinder14#IonChannel#SurreyUnipic.twitter.com/uf8wpnx2WN
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Our latest article "KCa1.1 and Kv1.3 channels regulate the interactions between fibroblast-like synoviocytes and T lymphocytes during rheumatoid arthritis" is now online: https://arthritis-research.biomedcentral.com/articles/10.1186/s13075-018-1783-9 …
#ionchannel
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