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#CKD chronic kidney disease is NOT a reason to avoid#allopurinol.#Gout#ACR19#RheumTwitter#MedTwitter#Rheumatology#Rheum#Arthritis#autoimmunepic.twitter.com/QRPc1LPkKA
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Research shows that
@TurmericPatent turmeric product works as effectively lowering uric acid levels compared to#allopurinol. Check out the figure comparing the results! pic.twitter.com/4oTZmJRMiU
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Yes!! The message is getting out: Updated
#gout guidelines: Don’t let kidney function dictate#allopurinol dosing | MDedge Rheumatology @ACRheumhttps://www.mdedge.com/rheumatology/article/213863/gout/updated-gout-guidelines-dont-let-kidney-function-dictate … -
The
#drugs that Gertrude B.#Elion (1918-1999) developed are used to treat a variety of maladies, such as#leukemia,#malaria, organ transplant rejection, as well as#herpes. 6-#mercaptopurine;#Azathioprine;#Allopurinol;#Acyclovir;#Nelarabine#histmed#pharmacology#sciencepic.twitter.com/Nhd5QnokrO
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Allopurinol dosing in CKD Start at 50 mg daily when eGFR <30 mL/ min; Increase by 50–100 mg every 2–5 wk until target uric acid reached;
#gout#allopurinol#treatment -
#allopurinol can cause hepatic granulomas in 2% of cases. Look out for elevated alk phos correlating with dose escalation of allopurinol and declining levels with discontinuation.#happythanksgivng#rheumatology#gout#medEd#rheumEd -
Excellent from Leanne Te Karu. Fix gout with allopurinol. Not diet.
#goutisgenetic#allopurinol https://twitter.com/etangata/status/1074019680849821696 … -
#Comorditiy is common in#gout & distinct#clusters form.#allopurinol can be safely be used in#ckd at higher than historically suggested doses. Uncertainty remains around association between gout &#neurodegeneration.#EULAR2019@GoutEducation@GoutandYou @PCSciences@elinlowripic.twitter.com/7z6ZkbnZRZ
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Compared to no treatment,
#allopurinol reduced serum urate, blood pressure and improved eGFR in children in a RCT@Kidney_Trialshttps://link.springer.com/article/10.1007/s00467-018-3943-1 … -
Our case report of
#allopurinol-related granulomatous hepatitis is out in@ACRheum The Rheumatologist. Very nicely written by Raj Vachhani.#gout@uabmedicine@uabimres@UABRheum@LisaWillett13@bhamjamo_md@KenSaag@SLB_Jr@maio_danila@VABIRMINGHAMhttps://www.the-rheumatologist.org/article/case-report-a-patient-with-gout-develops-granulomatous-hepatitis/ … -
Due to basically falling apart the last couple of months, & on me quacks advice, I’ve started my allopurinol one a day pills today. Pray to Baby Jebus it doesn’t trigger me gout of again.
#twistandshout#allopurinol -
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#Allopurinol is the preferred first-line agent. Even in advanced CKD. -Conditional recommendation to test for HLAB58*01 in African Americans with starting allopurinol. This one is the most controversial for me- I feel it could increase cost, restrict access to treatmentPrikaži ovu nit -
CARES RCT -
#febuxostat showed increase risk of CV death and Death from any cause. But when reviewing additional data in post hoc analysis, no difference in death when compared to#allopurinol.#Gout#ACR19#RheumTwitter#MedTwitter#Rheumatology#Rheum#Arthritis#autoimmunepic.twitter.com/yNZgKeRiOD
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@PCSciences Trishna Rathod-Mistry discusses important findings from her large PhD study, which shows
#allopurinol successfully reduces serum uric acid levels in#Gout but patients are not adherent#BSR19@DrJamesPriorpic.twitter.com/6RLzOGGGPk
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Pls RT. My friend in Detroit who died last week had Multiple Sclerosis. Dr gave her a drug that had horrible interaction w MS & Lupus meds that caused her to burn from inside out & resulted in organ failures. I was told it was
#Allopurinol for gout. I'm trying to get more info. -
It all sounds very daunting for
#febuxostat, up until you look at the numbers (15/1000 vs 11/1000 cv deaths with#allopurinol). Difficult to put it into perspective for the individual#gout patient...What are you doing in clinical practice?https://www.jwatch.org/fw115095/2019/02/25/fda-adds-boxed-warning-gout-drug … -
Last oral abstract in gout session
#ACR18: intense urate-lowering therapy (goal < 6 mg/dL) with#allopurinol in#gout prevents progression in CT-erosions, decreases#urate deposits when compared with no#urate target. Evidence for a treat-to-target approach@ACPinternists -
#Allopurinol Dose Escalation for#Gout Does Not Improve Mortality https://buff.ly/2xCDZPp pic.twitter.com/X7lBrTqlxh
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Found this
#trial very interesting: Cardiovascular Safety of#Febuxostat or#Allopurinol in Patients with#Gout, the older#drug outdoes the newer one among other lessons... http://www.nejm.org/doi/10.1056/NEJMoa1710895#.Wqb4aDoCYbA.twitter …#podagra#arthritis#heartattack#stroke#anginapic.twitter.com/mrpKYhzJhR
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