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#CNBCTV18Exclusive | Gland Pharma increases contract manufacturing of#Remdesivir, will now manufacture the drug for four companies, sources tell@ekta_batrapic.twitter.com/VYtsxw2Lux
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5/9
Key unknowns
Very few data on #remdesivir exposure in 1st trimester when organogenesis occurs No adverse findings in pre-clinical reproductive & developmental studiesZobrazit toto vlákno -
One more reason why we need an oral version of
#Remdesivir, like#GS441524...https://twitter.com/KatherineEban/status/1432401799886118913 … -
#CNBCTV18Exclusive | Sources say that Gland Pharma has increased contract manufacturing of#Remdesivir.@ekta_batra gets us the details.pic.twitter.com/sf6GPjHPVcEkta on Gland Pharma -
4/9
#Remdesivir was made available to
#pregnant patients through Gilead's compassionate use program while RCTs ongoing, but less comprehensive safety monitoring, limited follow-up & sparse data collection with these programs vs. RCT
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Group arrested for impersonating veteran politician also scored scarce remdesivir during the second wave and sold them in the black market at high prices.
@Mumbaikhabar9@mumbaimatterz#Sharadpawar#remdesivir https://twitter.com/mid_day/status/1430009468964671512 …pic.twitter.com/JBal7LfYqg
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6/9
Placental transfer?
Don't know, but #remdesivir hydrolyzed quickly so unlikely Active metabolites may have higher passage (some have long half-lives, low molecular weight, high free fraction, favoring passage)Zobrazit toto vlákno -
Is
#remdesivir still the go-to drug in PH? I really hope it’s not overpriced and are available to those who need it
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India is creating buffer stocks of critical meds for
#COVID19, to prepare for the impending third wave. Stocks of 15-odd#medicines incl#Remdesivir,#Tocilizumab & AmphotericinB will be maintained. This may prevent massive shortages & black marketing: my story@timesofindiapic.twitter.com/nkW4k29Yr3
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Our colleague Sara Vidlin is presenting UMC's analysis of reports on the
#COVID19 treatment#Remdesivir at#ICPE21 (23-25 Aug). View the poster in full and listen to her audio presentation here: http://ow.ly/KQVu50FWOHO@IntPharmacoEpipic.twitter.com/yO1aoBlNAT
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Tagging
@MattDavis138 our awesome coauthor for the#remdesivir
review 
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#Remdesivir sales will depend on the third wave of#COVID19, says Nithya Balasubramanian, Director at Sanford Bernstein. She tells@ekta_batra,@_soniashenoy &@SurabhiUpadhyay that the drug size is likely to shrink.pic.twitter.com/Htpftf1RmoNithya Balasubramanian -
Is there a clinical benefit to early or co-initiation of
#remdesivir relative to#dexamethasone compared to delayed introduction or non-users? Read Wong, et al’s findings here: https://doi.org/10.1093/cid/ciab728 …#IDTwitter#TwitteRx#CID#COVID19pic.twitter.com/lvY1zLWU3W
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In the first phase of
#COVID, antivirals like#remdesivir and monoclonal antibodies target the virus well. Treating the second phase, during which the immune response itself is the cause of whole-body organ damage, involves dampening the immune system. https://www.harvardmagazine.com/2021/09/feature-state-of-pandemic …pic.twitter.com/fY9kFHEzcN
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What do we know about
#remdesivir for#COVID19 in

#pregnant &#breastfeeding patients? Check out our review in@BSACandJAC@MattDavis138@StephenLap
https://academic.oup.com/jac/advance-article/doi/10.1093/jac/dkab311/6356837 …
on key points (but read the whole article too
)
1/9
#IDtwitter#obgyntwitter#TwitteRxpic.twitter.com/y2nEj86qlX
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New
#CochraneClinicalAnswer: What are the effects of#remdesivir for the treatment of#COVID19? https://buff.ly/3iyHdeK Based on the systematic review https://buff.ly/3jerRMK pic.twitter.com/rEYdgvPmK5
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#Remdesivir is the only Food and Drug Administration-approved drug for the treatment of#COVID19. Find our recommendations on using remdesivir with or without#dexamethasone here:http://go.usa.gov/xFGY3 -
Regeneron (REGN). Short term consolidation after breakout of large consolidation pattern. This is a new, fresh bull market.
#regeneron#remdesivir#Momentumpic.twitter.com/AWKZQNRnv5
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Happy to be participating in
#ICPE21! Visit our posters:
#Remdesivir Safety Monitoring During the#COVID19 Pandemic: http://ow.ly/KQVu50FWOHO
#Montelukast & Nightmare – Further Characterisation Using Data from#VigiBase: http://ow.ly/i52f50FWOU4 https://twitter.com/IntPharmacoEpi/status/1430139839236788244 …
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For those want an example of how “expertise” is trumped by due diligence, consider how a debutant
@victoriacyanide developed a better grasp of the PK/PD/tox of#remdesivir versus its simpler precursor,#gs441524, than the “experts”@GileadSciences.https://twitter.com/emmecola/status/1430249548648173570 …
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