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Osobe Vidi sve
@PLOSBiology PLOS Biology is a highly selective open-access, peer-reviewed general biology journal published by PLOS (http://plos.org )
San Francisco/ Cambridge, UK • plosbiology.org
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Ruh roh! Recurrent functional misinterpretation of RNA-seq data caused by sample-specific gene length bias
#PLOSBiology https://dx.plos.org/10.1371/journal.pbio.3000481 … -
I am so proud of this manuscript from our lab! For anyone interested in sex differences, metabolism, and fat storage, we've prepared a thread to highlight interesting and surprising findings from the paper!
@LiannaWat#PLoSBiology https://dx.plos.org/10.1371/journal.pbio.3000595 …Prikaži ovu nit -
Dating genomic variants and shared ancestry in population-scale
#sequencing data#genome#PLOSBiology: https://dx.plos.org/10.1371/journal.pbio.3000586 … -
#PLOSBiology: Single-cell transcriptomics of the naked mole-rat reveals unexpected features of mammalian ... https://dx.plos.org/10.1371/journal.pbio.3000528 … Our article describing the immune system of the long-lived and cancer-resistant naked mole-rat published@PLOSBiology today. A brief(ish) thread
pic.twitter.com/1LIbx5Gn2z
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Now officially out! The paper where we looked at single cells, animal and bacterial, inside living flies!
#PLOSBiology: Bellymount enables longitudinal, intravital imaging of abdominal organs and the gut microbiota ... https://dx.plos.org/10.1371/journal.pbio.3000567 … -
#PLOSBiology: Back-spliced RNA from retrotransposon binds to centromere and regulates centromeric chromatin l ... https://dx.plos.org/10.1371/journal.pbio.3000582 … -
Are there links between deforestation and environmental degradation as measured by Earth observations and the spread of infectious diseases such as malaria and dengue in the Brazilian Amazon?
#PLOSBiology https://dx.plos.org/10.1371/journal.pbio.3000526 … -
12-h clock - Frequency Intermodulation next step.
#PLOSBiology: 12-h clock regulation of genetic information flow by XBP1s https://dx.plos.org/10.1371/journal.pbio.3000580 … -
Some interesting thoughts on how to keep coding projects organized within a lab group.
#PLOSBiology: Best Practices for Scientific Computing https://dx.plos.org/10.1371/journal.pbio.1001745 … -
Interesting study suggesting that gene duplication limits expression noise while maintaining responsiveness. Delighted to see our "PCR Duplication" method from
@LabKnop at work.#PLOSBiology: Resolving noise–control conflict by gene duplication https://dx.plos.org/10.1371/journal.pbio.3000289 … -
Two years ago
@mas5050 published an article in#PLOSBiology https://plos.io/2qDezhi which invited readers to take part in an anonymous poll on the perception of non-native species in the conservation community. Here are the results:https://neobiota.pensoft.net/article/38741/ -
Alarmones ppGpp & pppGpp reshape the bacterial proteome by acting on DNA/RNA/protein synthesis. Study shows that ppGpp-bound IF2 prevents formation of 30S translation initiation complex; extent of ppGpp tolerance depends on the specific mRNA
#PLOSBiology https://plos.io/36JnXSN pic.twitter.com/zxGeGAuuny
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Circular
#retrotransposon RNAs generated by back-splicing bind to chromatin and mediate dynamic regulation of R-loops & centromeric chromatin loops in maize, driving centromeric#chromatin organization & CENH3 localization#PLOSBiology https://plos.io/2vtKUw4 pic.twitter.com/79pqk7zgw7
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Here's a link to the paper presented & discussed in today's
#CebibJournalClub#PLOSBiology: Recurrent functional misinterpretation of RNA-seq data caused by sample-specific gene length bi ... https://dx.plos.org/10.1371/journal.pbio.3000481 …Prikaži ovu nit -
Oh, my. This is quite cool. I didn't realize they were doing this on LIVE flies until I started reading the paper (ok, it does say it
). Individual cells can be observed.
Oh, my. There are clever people out there. #PLOSBiology https://plos.io/2U4ybui https://twitter.com/PLOSBiology/status/1222438983730372608 …
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Resistance to one
#antibiotic class often confers vulnerability to others; study of nitrofurantoin shows that this "collateral sensitivity" arises via a combo of mechanisms that can be exploited to combat#AntiMicrobialResistance#PLOSBiology https://plos.io/37wRv7i pic.twitter.com/zl1Z2lOx4u
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Groundbreaking
@Csaba_Pal_Lab and@Sommergroup revealed an Achilles heel of#AntibioticResistance: collateral super-sensitivity to other ABx! But how does the super-sensitivity work? https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3000612 … Strong effects arise from parallel mechanisms!@UAC_UU#PLOSBiology -
An adult
#FruitFly's abdomen is opaque, but "Bellymount" overcomes this problem, enabling imaging of live, intact flies at whole-organ & subcellular scales over multiple days (e.g. tracking of stem cell lineages & gut microbial colonization)#PLOSBiology https://plos.io/2U4ybui pic.twitter.com/iFbsJZz90E
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For some reason the article metrics think I've never shared this-so, a test- as if I wouldn't share our exciting project which dominated my 2019 & will reappear this year!
#PLOSBiology: Viewing the Invisible: Exploring common methodology across disciplines https://dx.plos.org/10.1371/journal.pbio.3000577 … -
Our paper relating
#frontostriatal#oscillations to vocal control in#bats just got accepted in#PlosBiology. Here is the preprint version, in case you missed it. Published version coming soon :) Fronto-striatal oscillations predict vocal output in bats https://www.biorxiv.org/content/10.1101/724112v1 …
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