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Check out our review in Cancer Discovery on factors that have limited the efficacy of
#PI3K inhibitors in solid tumors, and strategies to improve their impact. http://cancerdiscovery.aacrjournals.org/content/early/2019/03/13/2159-8290.CD-18-1175 … -
Excellent
#PI3K review by@RalitsaMadsen and@BartVanhaesebr1 from the@CellsigL lab at@scisignal@sciencemagazinehttps://stke.sciencemag.org/content/13/613/eaay2940 … -
Register and present your work at the Keystone Symposium on PI3K and PTEN http://www.keystonesymposia.org/20E1 May 3-7, 2020, Herrenhausen Palace, Hannover, Germany Discounted Abstract Deadline: Jan 7, 2020 Abstract Deadline: Feb 4, 2020
@KeystoneSymp#PI3K pic.twitter.com/e0OCVeDF9d
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Invasive
#fungal diseases in patients receiving#ibrutinib, other#BTK and#PI3K inhibitors for patients with#CLL and other hematological malignancies. Letter in@BloodJournal by Dr. Arbona-Haddad & team@DanaFarber: http://www.bloodjournal.org/content/131/17/1955/tab-e-letters …#aspergillosis#cryptococcosis#IFD -
Congrats to an awesome scientist, mentor, and role model, Lew Cantley from
@WeillCornell for being awarded the Horwitz Prize along with @DMSabatini Peter Vogt for the discovery of the#PI3K pathway in#cancer @Columbia#medtwitterhttps://www.cuimc.columbia.edu/news/horwitz-prize-awarded-work-critical-cancer-pathway … -
Happy to share our newest
@scisignal review on#PI3K, enjoy the read and@RalitsaMadsen 's PI3K accordion: https://stke.sciencemag.org/content/13/613/eaay2940 …. Best wishes to all for a wonderful New Year!pic.twitter.com/d4upypWUdC
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Differing cellular and environmental contexts produce distinct biological outcomes for
#PI3K signaling, according to a free Review of the past few decades of PI3K research from Madsen and Vanhaesebroeck.@uclcancer https://fcld.ly/m11sncx pic.twitter.com/6RtSpPyrpH
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Merry Christmas from CellSig

here is to another great #PI3K research year
pic.twitter.com/8PTpivFMZj
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Interesting paper which suggests diet may further enhance activity of
#pi3k inhibitors in the treatment of#cancer Diet boosts the effectiveness of a cancer drughttps://www.nature.com/articles/d41586-018-05871-x … -
#PI3K Pathway ReVisited: Distinct wiring in Non-Lymphoid vs Lymphoid | DaveFruman@UCIrvine@CellCellPress https://buff.ly/2vA0L8k pic.twitter.com/4TO7PNCxoU
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#PI3K Pathway ReVisited: Asymmetric Partitioning in Lymphocytes | DaveFruman@UCIrvine@CellCellPress https://buff.ly/2vSDd12 pic.twitter.com/cybxzxXciQ
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Lysine Specific Demethylase 1 (LSD1) promotes epithelial-mesenchymal transition via AKT in
#ColorectalCancer with a mutation in the catalytic subunit of#PI3K. Paper by Miller et al@GCDB_IU@IUMedSchool http://bit.ly/2SdOxy6 pic.twitter.com/PUAsDiOX6B
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Promise to stop churning out reviews for a bit now, but finally the published version of my Biochemical Society Transactions review on: "
#PI3K in#stemness regulation: from development to ##cancer" https://portlandpress.com/biochemsoctrans/article/doi/10.1042/BST20190778/222018/PI3K-in-stemness-regulation-from-development-to#.XjhVgW8E-Oc.twitter …pic.twitter.com/kQaAbaGbHe
Prikaži ovu nit -
Abstract deadline alert! Feb. 4
#PI3K &#PTEN in#CellGrowth &#VesicularTrafficking, hear@KlausOkken@harald_stenmark and more! http://bit.ly/KSpi3k20 Feb. 5#SingleCell Biology featuring@Eileen_Furlong@fabian_theis among others. http://bit.ly/KSsinglecell20 -
A bit late for bims-pideca on a Sunday but here it is - this week's papers of relevance to
#PI3K signalling in#development and#cancer. As always thanks to@BiomedNew! http://biomed.news/bims-pideca/2020-02-02 … -
Brain tumours manipulate neighbouring synapses https://www.nature.com/articles/d41586-020-00137-x …
@nature#glia#braincancer#PIK3CA#PI3K https://www.nature.com/articles/s41586-020-1952-2 … => how#glioblastoma alters the neuronal microenvironment:#Glypican (GPC3) promotes tumorigenesispic.twitter.com/WKmH1bGAmu
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Congratulations to our professor, Lew Cantley, as well as to
@DMSabatini and Peter Vogt for receiving the Louisa Gross Horwitz Prize at@Columbia! Great photo btw...#PI3K#mTORpic.twitter.com/zPm78HGNG0
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Happy to finally see our new review on the relevance of
#PI3K inhibitors in#breastcancer. Great job by @EnedaToska and @VasanNeil, real experts in the field. @sloan_kettering @Annals_Oncologyhttps://academic.oup.com/annonc/article/30/Supplement_10/x3/5681697 … -
Take a look at our NEW Review by
@Gerta_Hoxhaj &@Manning_BD, discussing the#PI3K –AKT signalling network and its control of#cancer cell#metabolism through regulation of nutrient transport and metabolic enzymes. http://go.nature.com/2NIic04@NatResCancer#cancermetabolismpic.twitter.com/YeN4M4Bnso
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