Rezultati pretraživanja
  1. 14. sij

    from my group developed hifiasm, a new assembler that preserves local phasing. Human asm in 1/2 day. Tested on non-humans. Comparable asm quality to others. Features in plan: consistent primary asm & global phasing. Feedback welcomed!

  2. 4. ruj 2019.

    PSA! HiFi = library prep & data type CCS = sequencing mode & read consensus analysis So, we'd say “I made a HiFi library, sequenced it in CCS mode, and ran the raw data through CCS analysis to get my for variant calling”. You’re welcome. ✌️

  3. 13. kol 2019.
  4. 18. lis 2019.

    Awesome collaboration with Shilpa Garg and many others. Really the next level of fast and automated diploid human assemblies. Requiring and Hi-C reads. Awesome talk yesterday .

  5. 8. lis 2019.

    Evan Eichler talking about HiFi reads at AGTA2019. Game changer!

  6. 25. sij
    Odgovor korisnicima i sljedećem broju korisnika:

    Using the price list from (a CSP), a library prep and 30 hr Sequel II movie comes in right about $5000 for an external researcher. Arabidopsis can be run 5-7-plex, for a comparable or lower cost per sample

  7. 15. sij
    Odgovor korisnicima

    And the make assemblies this large easier than ever. The bulk of the computation is the CCS job, which scales linearly with genome size and coverage. That replaces a massive preassembly job, which scales quadratically.

  8. 27. sij
    Odgovor korisnicima i sljedećem broju korisnika:

    Yep, definitely polish any CLR or ONT assembly, but it sure is nice to get it right the first time (and save a bunch of time, effort, and money) if you can design your experiment to use .

  9. 14. sij

    Happy to see there’s a new version of canu for by et al. That’s three new genome assemblers announced during . Hifi assembly is a game changer for genomics.

  10. 15. kol 2019.

    Oooh, want to put up against regular long read data in a human, an animal, and a plant?

  11. 16. lis 2019.

    Still time to learn more about all things , especially . Lanier A/B

  12. 17. lis 2019.

    Stop by the booth 1020 today to talk accurate and affordable long-read sequencing. Learn about and our new Sequel II System.

  13. 25. ruj 2019.

    JK: Yowza! This new 2.0 chemistry on the Sequel II is generating a LOT of 15kb .

  14. 16. lis 2019.

    EH: Very recently, we’ve started to recommend for de novo human genome assemblies that are both highly accurate and phased into haplotypes, with faster compute times! Talk to in the poster session (#1692) to find out more!

  15. 17. lis 2019.

    Shilpa Garg shows phased generate human assemblies with QVs > 55, and NG50 >25Mb. Methods on github. What an all star team! and more!

  16. 17. lis 2019.
    Odgovor korisnicima

    Hi Phil, are already released for Sequel 2. I like your circularity pun 🙂. This website is a nice overview of the tech:

  17. 16. sij

    Check out the blog summary of this recent preprint featuring fully phased human genome assemblies w/o trio sequencing: Strand-seq +

  18. 18. lis 2019.

    Well that’s that. Thanks to all who came to see us at to discover that can help advance your science with affordable, highly accurate long-read sequencing data you can trust.

  19. 15. sij

    Well that all happened in the blink of an eye. Thanks to everyone who stopped by at to talk and . See you next year!

  20. prije 15 sati

    Haplotype Diversity and Sequence Heterogeneity of Human Telomeres great preprint by from using

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