Fascinating that individual tissues would have variable sensitivities to the same oncogenes. I wonder if the effect of tissue micro environment (and “local immune system”) is under-appreciated here
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@DrSidMukherjee wrote an essay about this, memorably terming it the dynamics of "seed and soil." You could look it up. The New Yorker, probably. - 1 more reply
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It's almost as if those cells have different 'fates', isn't it?
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