Links for stuff I may've mentioned this weekend: - Chromosome selection: https://www.gwern.net/Embryo-selection#fn6 … - selection unlimited: https://www.gwern.net/Embryo-selection#limits-to-iterated-selection-the-paradox-of-polygenicity … - Catnip: https://www.gwern.net/Catnip - Advertising A/B test: http://www.gwern.net/Ads - Anti-spaced-repetition: https://www.gwern.net/Statistical-notes#program-for-non-spaced-repetition-review-of-past-written-materials-for-serendipity-rediscovery-archive-revisiter …
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- why no better nicotines? https://www.reddit.com/r/researchchemicals/comments/4nsniu/why_no_nicotinic_rcs/ … https://www.reddit.com/r/Nootropics/comments/4ojwhr/targeting_nicotinic_receptors_for_nootropics/ … - why are math proofs usually wrong but results right? https://www.gwern.net/The-Existential-Risk-of-Mathematical-Error … - why Gmail won't offer spam-filter-as-a-service: https://www.gwern.net/Complement - LSD u-dosing doesn't work: http://www.gwern.net/LSD-microdosing
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Replying to @gwern
Your microdose was too small. I don't know what the correct dose is for you but there's a wide range between imperceptible and hallucinogenic that gives noticeable effects on mood. You should have experimented to find the correct dose before doing the experiment.
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Replying to @Minthos_
And yet, lack of sequential dose-finding experimental design somehow doesn't stop almost all microdosers from immediately reporting wide-ranging benefits from unmeasured & variable doses nor are there any priors for knife-edge dose-response curves like suggested.
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Replying to @gwern
So based on nothing you decide it's all bunk because your own experiment was bunk. I'm all for reporting negative results and I like the way you did your experiment but now you're just pulling conclusions out of your ass. You're no better than them.
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Replying to @Minthos_
And what should we call pulling out post hoc excuses to save the appearances like 'oh you just didn't use the right dose'?
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Replying to @gwern
Save appearance? I'm just calling you out on your hypocrisy. You identified a dosage (guesstimated to around 8 ug or so) that had no measurable effect on you. You identified another dosage (150 ug or so) that had a strong effect on you.
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Which are supposed to be about different things. Having no effect is exactly what the standard model 'LSD just makes you hallucinate' predicts. It's *not* what microdosers predict, who claim entirely different regime of effects in the sub-perceptual area.
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