I think sometimes about the fact that Jeanne Calment has been the oldest human ever for almost my entire life, has held it for the past 17 years after dying 122yo, the closest runner up so far was still 3 years younger, and the current oldest human is only 115. (And she smoked.)
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Calment is just a weird weird weird outlier in GRG... Context here is thinking about embryo selection & life expectancy GWASes: https://www.biorxiv.org/content/early/2018/07/06/363036 … Looks like you could easily increase life expectancy by half a year using embryo selection and current PGSes? Not bad!
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(I dumped the estimate into https://www.gwern.net/Embryo-selection#multiple-selection-on-genetically-correlated-traits … if you're curious where 'half a year' comes from, exactly.)
8:56 PM - 15 Oct 2018
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