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Prikvačeni tweet
The combination of fragment-based drug discovery and SHAPE will likely enable development of drugs that target specific RNA molecules with high affinity. https://lnkd.in/epdkTqv pic.twitter.com/eRXsVAmMhA
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Dave Grawoig, Ph.D. proslijedio/la je Tweet
You'll find this article to be fascinating! It may explain why the virus is spreading so easily in Asia. Asian males may express more ACE2 receptors on their alveolar cells, creating more attachment sites for the novel coronavirus.https://www.biorxiv.org/content/10.1101/2020.01.26.919985v1.full …
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Dave Grawoig, Ph.D. proslijedio/la je Tweet
replenishing helpful bacteria...
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Dave Grawoig, Ph.D. proslijedio/la je Tweet
cellular level, whoops
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Dave Grawoig, Ph.D. proslijedio/la je Tweet
interesting photo
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Dave Grawoig, Ph.D. proslijedio/la je Tweet
"SARS, or severe acute respiratory syndrome, is also caused by a coronavirus, and the older pathogen bears much resemblance to the newly emerged one. "
$ABBVhttps://www.fiercepharma.com/pharma-asia/china-repurposes-abbvie-hiv-dug-as-big-pharma-rallies-to-help-combat-deadly-coronavirus …Prikaži ovu nitHvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
Dave Grawoig, Ph.D. proslijedio/la je Tweet
While no specific remedy has been found for the novel #coronavirus, 7 small-molecule drugs, specifically targeting the RNA polymerase and protease of 2019-nCoV are currently in clinical research, renowned Chinese SARS fighter#ZhongNanshan said on Sunday to Xinhua.#nCoV2019pic.twitter.com/MBMIwhIxMt
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Dave Grawoig, Ph.D. proslijedio/la je Tweet
Flu, HIV, and coronavirus are all retroviruses. All use a protein called reverse transcriptase to convert viral RNA into DNA, and another enzyme to patch it into the infected cell's DNA. Drugs that target these proteins may be effective for all three.
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Dave Grawoig, Ph.D. proslijedio/la je Tweet
Actually, it makes sense physiologically & they're doing studies on it: http://genomed.com/pdf/AT1RSARS.pdf …
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Dave Grawoig, Ph.D. proslijedio/la je Tweet
Supplementary information: https://static-content.springer.com/esm/art%3A10.1038%2Fs41586-020-2008-3/MediaObjects/41586_2020_2008_MOESM1_ESM.pdf …
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Dave Grawoig, Ph.D. proslijedio/la je Tweet
In this paper, researchers have presented a metagenomic RNA sequencing of WH-Human-1
#coronavirus, showing that the virus was most closely related to a group of SARS-like coronaviruses previously sampled from bats in China. https://www.nature.com/articles/s41586-020-2008-3_reference.pdf …pic.twitter.com/NuMLnWAeNA
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Dave Grawoig, Ph.D. proslijedio/la je Tweet
Researchers used Direct-zol to extract RNA from the coronavirus: https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(20)30183-5/fulltext … If you are studying the Wuhan coronavirus, please don't hesitate to contact us for assistance, we are ready to help.
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Dave Grawoig, Ph.D. proslijedio/la je Tweet
‘Striking’ coronavirus mutations found within one family cluster, Chinese scientists sayhttps://www.scmp.com/news/china/science/article/3048772/striking-coronavirus-mutations-found-within-one-family-cluster?utm_term=Autofeed&utm_medium=Social&utm_content=article&utm_source=Twitter#Echobox=1580747338 …
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Dave Grawoig, Ph.D. proslijedio/la je Tweet
Evidence emerging that the new
#coronavirus
seems to mutate rather fast. Authors say “Close monitoring of the virus’s mutation, evolution, and adaptation is needed”. In a family of 6 infected people, 2 ‘nonsynonymous’ mutations occurred during human-to-human transmission.
https://twitter.com/scmpnews/status/1224369637443457030 …Prikaži ovu nitHvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
Dave Grawoig, Ph.D. proslijedio/la je Tweet
"Evidence emerging that the new
#coronavirus seems to mutate rather fast." They're RNA viruses! That's what RNA viruses DO! https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6107253/ … https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3857799/ …#2019nCoV#scicommhttps://twitter.com/DrEricDing/status/1224380417047977984 …Hvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
Dave Grawoig, Ph.D. proslijedio/la je Tweet
“Philosophers, psychologists, doctors, writers could have observed in our camps ... the specific process of narrowing of man's mental and intellectual horizon, decline of a man to the level of an animal and his process of dying alive.”
#TheGulagArchipelago#SolzhenitsynHvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
Dave Grawoig, Ph.D. proslijedio/la je Tweet
It was reported one doctor had died of a heart attack at one point but the links now about the recorded doctor seem vague in my search results
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Dave Grawoig, Ph.D. proslijedio/la je Tweet
You Do not make any sound
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Dave Grawoig, Ph.D. proslijedio/la je Tweet
Calorie restriction dampens inflammation of aging through increased autophagy. https://www.mdpi.com/2073-4409/9/1/82/htm …pic.twitter.com/GEQ4l65irf
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Dave Grawoig, Ph.D. proslijedio/la je Tweet
Association of adult lung function with accelerated biological aging Good news for me: several years ago my lung function was estimated in the top 1% despite years of cigarettes in my wayward youth.https://www.aging-us.com/article/102639/text …
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Dave Grawoig, Ph.D. proslijedio/la je Tweet
Why Antibiotic Resistance Is Ignored by Big Pharma
@TuftsCIMAR @TuftsMedicalCtr @IDSAInfo @WinterCourseID @CARB_X @Wellcome_AMRhttps://www.menshealth.com/health/a30715597/antibiotic-resistance-drug-companies/ …Hvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi
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