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grahamwalker's profile
𝗚𝗿𝗮𝗵𝗮𝗺 𝗪𝗮𝗹𝗸𝗲𝗿, 𝗠𝗗
𝗚𝗿𝗮𝗵𝗮𝗺 𝗪𝗮𝗹𝗸𝗲𝗿, 𝗠𝗗
𝗚𝗿𝗮𝗵𝗮𝗺 𝗪𝗮𝗹𝗸𝗲𝗿, 𝗠𝗗
@grahamwalker

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𝗚𝗿𝗮𝗵𝗮𝗺 𝗪𝗮𝗹𝗸𝗲𝗿, 𝗠𝗗

@grahamwalker

Emergency MD in SF; Creator @mdcalc; Tweets = my own/not employers'. Not a hero, just a well-trained human. So, so tired of COVID. #GetVaccinated 💉

San Francisco, CA
mdcalc.com
Joined July 2007

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    𝗚𝗿𝗮𝗵𝗮𝗺 𝗪𝗮𝗹𝗸𝗲𝗿, 𝗠𝗗‏ @grahamwalker Jul 28

    Oh boy oh boy oh boy. It's not every day I get to take down a completely un-researched, un-fact-checked @opinionwsj piece. But this, Twitter, is a *doozy*. It's clear the authors have read ZERO of the literature on ivermectin (IVM). Thread incoming 🧵: https://www.wsj.com/amp/articles/fda-ivermectin-covid-19-coronavirus-masks-anti-science-11627482393?st=licozv23q1oy2dd&reflink=article_email_share …

    2:30 PM - 28 Jul 2021
    • 426 Retweets
    • 1,050 Likes
    • lovingANDliving Trevor Woller Frederica Huxley Jazzy 🌵 Lordy there ARE tapes! Ian Ross CarolinaByTheMoon 🏈🏀🏐 Fortitude Dr. J Risher D.
    83 replies 426 retweets 1,050 likes
      1. New conversation
      2. 𝗚𝗿𝗮𝗵𝗮𝗺 𝗪𝗮𝗹𝗸𝗲𝗿, 𝗠𝗗‏ @grahamwalker Jul 28

        First, the authors use the trope that "ivermectin won a Nobel Prize" [for parasites], so I guess that means it's good? Several drugs have won Nobels: Artemisinin; propranolol. Should they be used for COVID? (They should not.) https://www.nobelprize.org/prizes/medicine/2015/press-release/ …https://www.nobelprize.org/prizes/medicine/1988/press-release/ …

        14 replies 28 retweets 225 likes
        Show this thread
      3. 𝗚𝗿𝗮𝗵𝗮𝗺 𝗪𝗮𝗹𝗸𝗲𝗿, 𝗠𝗗‏ @grahamwalker Jul 28

        𝗚𝗿𝗮𝗵𝗮𝗺 𝗪𝗮𝗹𝗸𝗲𝗿, 𝗠𝗗 Retweeted 𝗚𝗿𝗮𝗵𝗮𝗺 𝗪𝗮𝗹𝗸𝗲𝗿, 𝗠𝗗

        Next, they quote the pro-IVM group FLCCC saying ivermectin is very safe. And in the doses used for parasites, I agree. But the doses the FLCCC recommends are about 12✖️ higher than what is given for parasitic infections. There's no safety data known yet.https://twitter.com/grahamwalker/status/1419723800069828608 …

        𝗚𝗿𝗮𝗵𝗮𝗺 𝗪𝗮𝗹𝗸𝗲𝗿, 𝗠𝗗 added,

        𝗚𝗿𝗮𝗵𝗮𝗺 𝗪𝗮𝗹𝗸𝗲𝗿, 𝗠𝗗 @grahamwalker
        Replying to @peterpham @GidMK
        If you can provide me with the agreed-upon dosage and frequency in all of the trials, I’m happy to look. Dosages and frequencies are all over the map. And generally the doses for river blindness are much much lower and much less frequent. pic.twitter.com/pKXkw8OxTE
        4 replies 23 retweets 158 likes
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      4. 𝗚𝗿𝗮𝗵𝗮𝗺 𝗪𝗮𝗹𝗸𝗲𝗿, 𝗠𝗗‏ @grahamwalker Jul 28

        (Now we're getting to the good stuff.) They tell us that IVM kills COVID. Wow! They link to research (👍). But for some reason, they leave out that this was a) in a petri dish, not in an animal 🐭 b) lots of things kill COVID in a petri dish (bleach, soap, a microwave) and...

        13 replies 47 retweets 302 likes
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      5. 𝗚𝗿𝗮𝗵𝗮𝗺 𝗪𝗮𝗹𝗸𝗲𝗿, 𝗠𝗗‏ @grahamwalker Jul 28

        c) The concentrations required to kill COVID aren't easily or safely possible in humans even taking very high dosages, as reported by many, MANY scientists: https://www.ijidonline.com/article/S1201-9712(21)00535-X/fulltext … https://ascpt.onlinelibrary.wiley.com/doi/full/10.1002/cpt.1889 … https://d197for5662m48.cloudfront.net/documents/publicationstatus/34100/preprint_pdf/ccd805fd2383b5a138b3724ed98a8c5d.pdf … https://d197for5662m48.cloudfront.net/documents/publicationstatus/34103/preprint_pdf/b47c0e4b659e60e08dda603b06ba11b3.pdf …

        8 replies 21 retweets 213 likes
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      6. 𝗚𝗿𝗮𝗵𝗮𝗺 𝗪𝗮𝗹𝗸𝗲𝗿, 𝗠𝗗‏ @grahamwalker Jul 28

        (They then refer to 70 trials for ivermectin, but don't link to a reference; they ignore that one of the larger trials just got retracted for possible fraud; they do not report that the trials are generally very low quality.) @JackMLawrence @gidmkhttps://www.theguardian.com/science/2021/jul/16/huge-study-supporting-ivermectin-as-covid-treatment-withdrawn-over-ethical-concerns …

        3 replies 26 retweets 203 likes
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      7. 𝗚𝗿𝗮𝗵𝗮𝗺 𝗪𝗮𝗹𝗸𝗲𝗿, 𝗠𝗗‏ @grahamwalker Jul 28

        🆗 Now it gets WEIRD: They cite a study (but don't link to it; I will) that is one of the worst IVM studies to cite. It says it is a "retrospective study" that enrolled patients and gave them IVM. (You cannot do that unless you have a time machine.) 🕰https://www.archbronconeumol.org/en-ivermectin-treatment-may-improve-prognosis-articulo-S030028962030288X?newsletter=true&coronavirus#:~:text=This%20study%20shows%20that%20ivermectin,7%E2%80%9312%20days13 …

        5 replies 18 retweets 198 likes
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      8. 𝗚𝗿𝗮𝗵𝗮𝗺 𝗪𝗮𝗹𝗸𝗲𝗿, 𝗠𝗗‏ @grahamwalker Jul 28

        2nd, The study was not randomized at all, which means there's lots of possible bias. 3rd, The study only gave 1, relatively low-dose of IVM (12mg once), IVM proponents talk a lot about higher doses being "better." We don't really even know what a "right" dose even is.

        2 replies 11 retweets 142 likes
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      9. 𝗚𝗿𝗮𝗵𝗮𝗺 𝗪𝗮𝗹𝗸𝗲𝗿, 𝗠𝗗‏ @grahamwalker Jul 28

        4th, OF COURSE the IVM patients did better, they weren't as sick! 10% vs 46% needed oxygen even before they got ivermectin. So OF COURSE fewer of them needed the ICU and fewer died. And so OF COURSE you're gonna stay in the hospital longer if you're in the ICU.pic.twitter.com/KuJf3zf6Qp

        8 replies 12 retweets 159 likes
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      10. 𝗚𝗿𝗮𝗵𝗮𝗺 𝗪𝗮𝗹𝗸𝗲𝗿, 𝗠𝗗‏ @grahamwalker Jul 28

        Then they cite but again don't link to a paper by Shouman in Egypt suggesting IVM prevented family transmission of COVID but with many issues, including the fact that they didn't actually confirm people had COVID, just had COVID symptoms instead. https://clinicaltrials.gov/ProvidedDocs/61/NCT04422561/Prot_SAP_000.pdf …

        3 replies 11 retweets 130 likes
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      11. 𝗚𝗿𝗮𝗵𝗮𝗺 𝗪𝗮𝗹𝗸𝗲𝗿, 𝗠𝗗‏ @grahamwalker Jul 28

        Now it just gets awkward. They discuss a trial that reported in 200 healthcare workers, "only 2% of those given ivermectin developed Covid-19." This study, crazy enough, was retracted last week (see Guardian link, above). How can these authors not have known this?!? 🤯

        3 replies 18 retweets 170 likes
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      12. 𝗚𝗿𝗮𝗵𝗮𝗺 𝗪𝗮𝗹𝗸𝗲𝗿, 𝗠𝗗‏ @grahamwalker Jul 28

        ⚠️I'm surprised that they then promote the idea that ivermectin is safe in pregnant women⚠️, when the only data I've seen essentially concludes "we don't know," and *especially* we don't know in the dosages recommended by the FLCCC. Very irresponsible.https://www.thelancet.com/journals/langlo/article/PIIS2214-109X(19)30453-X/fulltext …

        4 replies 16 retweets 154 likes
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      13. 𝗚𝗿𝗮𝗵𝗮𝗺 𝗪𝗮𝗹𝗸𝗲𝗿, 𝗠𝗗‏ @grahamwalker Jul 28

        This whole thing is seriously weird. The authors conclude by questioning the FDA mentioning masking, distancing, hand washing, and avoiding crowds, and then imply that these things shouldn't be done unless "double-blind studie[d]." Or at least that there's a double standard.

        6 replies 11 retweets 140 likes
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      14. 𝗚𝗿𝗮𝗵𝗮𝗺 𝗪𝗮𝗹𝗸𝗲𝗿, 𝗠𝗗‏ @grahamwalker Jul 28

        And very extremely ironically, despite mentioning multiple studies in their poorly-researched Op-Ed for the WSJ, not a single one of them in double-blinded. (+100 irony points, the best double-blind RCT of IVM showed no benefit.)https://jamanetwork.com/journals/jama/fullarticle/2777389 …

        10 replies 14 retweets 174 likes
        Show this thread
      15. 𝗚𝗿𝗮𝗵𝗮𝗺 𝗪𝗮𝗹𝗸𝗲𝗿, 𝗠𝗗‏ @grahamwalker Jul 28

        𝗚𝗿𝗮𝗵𝗮𝗺 𝗪𝗮𝗹𝗸𝗲𝗿, 𝗠𝗗 Retweeted Jeremy Farrar

        Finally: The Cochrane Group, a highly respective research collaborative came out with its ivermectin meta-analysis today, without suggestion of benefit at this time. Pretty damning.https://twitter.com/JeremyFarrar/status/1420333684192907277 …

        𝗚𝗿𝗮𝗵𝗮𝗺 𝗪𝗮𝗹𝗸𝗲𝗿, 𝗠𝗗 added,

        Jeremy FarrarVerified account @JeremyFarrar
        Ivermectin for preventing and treating COVID‐19 - Popp, M - 2021 | Cochrane Library @cochranecollab https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD015017.pub2/full#.YQE0BQayS2c.twitter …
        Show this thread
        8 replies 28 retweets 226 likes
        Show this thread
      16. 𝗚𝗿𝗮𝗵𝗮𝗺 𝗪𝗮𝗹𝗸𝗲𝗿, 𝗠𝗗‏ @grahamwalker Jul 28

        cc @RealIvermectin @fullydavid @WisdomRebel @gorskon @CriticalCareNow @mpanhwar92 @TheSGEM @rafidah72 @EricTopol @VPrasadMDMPH @ZDoggMD @JeremyFarrar @cochranecollab

        6 replies 4 retweets 62 likes
        Show this thread
      17. 𝗚𝗿𝗮𝗵𝗮𝗺 𝗪𝗮𝗹𝗸𝗲𝗿, 𝗠𝗗‏ @grahamwalker Jul 29

        Ivermectin/anti-vaxx trolls starting to show up. I'm happy to engage anyone in a critique of my interpretation of the evidence/research/papers that the authors cite, or other IVM evidence. But so far your arguments of "Ivermectin works! You're a bad doctor!" don't do much for me.

        8 replies 5 retweets 153 likes
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      18. 𝗚𝗿𝗮𝗵𝗮𝗺 𝗪𝗮𝗹𝗸𝗲𝗿, 𝗠𝗗‏ @grahamwalker Jul 29

        Correction issued by @WSJopinion as Elgazzar study was retracted. They admit they relied on "a summary of studies" — it's the FLCCC meta-analysis — and did not read individual studies themselves. 👎👎👎 Why no correction from you, @AmJThera? https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8088823/ …pic.twitter.com/i4xmT7g1xd

        10 replies 3 retweets 79 likes
        Show this thread
      19. End of conversation

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