Well, to be devil’s advocate, there was a time that the world being round or landing on the moon seemed “implausible.” In an age of loss of faith in science, valid concerns about peer-review or industry influence or profit motive, scientists need to cultivate more humility.
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I have done 2 reviews lately for chronic pain talks and agree with this completely. I am surprised that the physicians who are such strong advocates for efficacy are handing their hats in such weak studies Bias seems clear

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The endocannabinoid system is one of the most significant neurological discoveries, so recent and still not fully researched, it hasn't been a significant part of the medical curriculum. That is why you are saying these things. "Smoking" -- that's revealing.
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It may be a revelation someday that endocannabinoid system may prove significant advance ......no argument there....but just like any other scientific research there has to be verifiable and reproducible proof of efficacy before benefit can be claimed. Not different standard.
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I don’t have an opinion on marijuana itself. Generally pediatricians are cautious about the impact on developing brains. My point is that It is something previously criminalized, for which people are sitting in jail even, that now some states are issuing licenses for.
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