Something worth noting - no matter how you look at it, the research community has royally fucked up when it comes to ivermectin
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Yes, there are endless terrible trials, but we've had 18 months. WE COULD'VE RUN GOOD TRIALS We didn't. That is woeful, and frankly inadequate
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We spent endless billions researching hydroxychloroquine, and knew by August 2020 that it didn't work, but ivermectin which has been given to 100s OF MILLIONS OF PEOPLE...still no answer. Shameful
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Replying to @GidMK
I would argue that we actually *do* know, with approximately as much certainty as we had a year ago for
#HydroxyChloroquine, that#Ivermectin almost certainly doesn’t work. Low prior probability + equivocal clinical trials = doesn’t work.9 replies 8 retweets 61 likes -
Replying to @gorskon
Sure, but we could've easily had a large trial really testing the idea by now. If we'd rolled it into RECOVERY or SOLIDARITY, it might've prevented (or caused) literally millions of people to get the drug
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We're still arguing about awful, low-quality evidence, but as a global research community that is a choice. We could definitely have tested this properly by now, and we really dropped the ball
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At some point isn't it unethical to try something you don't think will work just to shut people up?
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Correct. If it weren't for the grifters and the craze promoting #HydroxyChloroquine, preliminary evidence would have been so weak that under any normal circumstances no one would have thought it worth testing in large RCTs. The same applies to #ivermectin.
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