Notable that one of the leading physician advocates for using ivermectin for COVID-19, Paul Marik, was once also convinced that he had cured sepsis with a combination of vitamins and steroids — a finding not replicated once a randomized trial was actually performed. /Thread
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His words: "We haven't seen a patient die of sepsis since we began using the combination therapy a year ago. We have completely changed the natural history of sepsis."https://www.nbc12.com/story/34986689/virginia-doctors-possible-cure-could-save-millions-from-sepsis/ …
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He's a member of the FLCCC Alliance, along with Pierre Kory, who testified in the Senate for Ron Johnson that Ivermectin is "effectively a 'miracle drug' against COVID-19." Ivermectin is not the only FLCCC Alliance's recommendation that is not evidenced-based.
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For instance, here's their "Long COVID" protocol, which calls for treatment (on the basis of little to no evidence) with: -Ivermectin -Steroids -"Treatment of Suspected Mast Cell Activation" (various agents) -"Macrophage/Monocyte Repolarization Therapy" (various agents)pic.twitter.com/x6MkSontPg
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One can disagree about role that social media companies should (or shouldn't) play in censoring misinformation — I fall more on the ACLU end of the spectrum — but the push by
@BretWeinstein & others to cast ivermectin as a suppressed miracle cure is goofy, and indeed harmful.3 replies 10 retweets 87 likesShow this thread -
A large, high-quality trial can be conducted. If benefit is demonstrated (and a priori that's improbable with such a re-purposed drug), that would be wonderful! But based on where things stand now, these individuals, including critical care doctors, are making extraordinary, ...
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... indeed grandiose claims that is simply not backed by adequate evidence, both for ivermectin and their "protocols" more broadly. It's grossly irresponsible.
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It's not at all surprising that this happened- earlier with hydroxychloroquine and now with ivermectin. The "allure of the miracle cure" exerts such a strong pull - both patients and physicians are potentially prone to perceive such a cure based on narrow reading, or experience
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Replying to @awgaffney
I could understand how
#hydroxychloroquine rose to prominence. It was early in the pandemic. ICUs were besieged with incredibly sick people, who were dying in droves. Doctors didn't know what to do. Here was this cheap drug, recommended by China. Why not?2 replies 1 retweet 7 likes -
Replying to @gorskon @awgaffney
I can (sort of) understand how in March-April 2020, when the pandemic really took off in the US, it could *seem* that there was nothing to lose by trying HCQ. There was nothing else. That HCQ was quickly shown not to work by fall was science correcting itself.
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What I don't understand is how the same thing can happen now. There are grifters out there still promoting HCQ as a miracle cure for #COVID19. They're often the same grifters now promoting #ivermectin as a miracle cure.
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Replying to @gorskon @awgaffney
We now have much better supportive treatment for
#COVID19. Mortality is lower. It's not good enough, but it's nowhere near as desperate as the situation was 15 months ago. AND we now have safe and effective#COVIDVaccines, to boot!0 replies 1 retweet 9 likesThanks. Twitter will use this to make your timeline better. UndoUndo
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