Persistent viral antigens will be dispersed within the tissues of the naturally infected. The idea is that upon reactivation of the antigen specific T-cells by the vaccine, these antigen-bearing tissues will be targeted leading to recurrent inflammatory state - deadly to some.
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Replying to @noorchashm @ASRothstein and
My question remains. Why would the vaccine be more dangerous than a second exposure to the actual virus?
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Replying to @JHowardBrainMD @ASRothstein and
Second exposure to a natural virus in an immune person is innocuous bc the person is usually immune. So the virus is neutralized and never takes hold. The vaccine forces the immune response because antigens are delivered in immunogenicity form via injection along w adjuvant.
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Replying to @noorchashm @JHowardBrainMD and
the mRNA vaccines do not contain an adjuvant
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Replying to @mcfunny @JHowardBrainMD and
mRNA is a self-adjuvant...actually.
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Replying to @noorchashm @mcfunny and
The virus contains mRNA. You are positing that the mRNA in the vaccine is dangerous but the mRNA in the virus is harmless. This makes so sense to me.
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Replying to @JHowardBrainMD @noorchashm and
I thought that the mRNA in the vaccine was made with modified bases to reduce immunogenicity.
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Replying to @mcfunny @JHowardBrainMD and
It is. The modified bases not only stabilize the mRNA but also decrease its immunogenicity.
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Negative. The mRNA vaccine is quite specifically immunogenic. Because of its mechanism of action. It is likely to be one of the most, if not the most, powerful and effective vaccine we've ever made. That does not make it intrinsically safer for every human being. Think Dave!
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Replying to @noorchashm @mcfunny and
I was referring to the immunogenicity of the RNA itself. The liposomes themselves do have immunogenic properties. Think, Hooman!
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David Gorski, MD, PhD Retweeted R Marcucio
Here's what I mean regarding the modified bases in the mRNA.https://twitter.com/mcfunny/status/1367139068144836608?s=20 …
David Gorski, MD, PhD added,
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