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gorskon's profile
David Gorski, MD, PhD
David Gorski, MD, PhD
David Gorski, MD, PhD
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@gorskon

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David Gorski, MD, PhDVerified account

@gorskon

Surgeon/scientist promoting science in medicine and exposing quackery. Editor of Science-Based Medicine. My opinions do NOT represent those of my employers.

Michigan, USA
sciencebasedmedicine.org
Joined October 2009

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    1. David Gorski, MD, PhD‏Verified account @gorskon 24 Oct 2020
      Replying to @keithlaw @leeloyd1 and

      RCTs are the gold standard, yes.

      1 reply 0 retweets 9 likes
    2. David Gorski, MD, PhD‏Verified account @gorskon 24 Oct 2020
      Replying to @gorskon @keithlaw and

      HOWEVER, that doesn’t mean that, when RCTs are either impractical or unethical (e.g., an RCT of vaccinated vs. unvaccinated children, which would leave the control group vulnerable to vaccine-preventable disease), we can’t still make strong conclusions from other study designs.

      2 replies 2 retweets 16 likes
    3. Nick Gorton, MD  🏳️‍🌈 🐾‏ @RNickGorton 24 Oct 2020
      Replying to @gorskon @doritmi and

      Or NAC as an antidote to acetaminophen. No RCTs to support that. But before we used NAC OD of 180mg/kg was uniformly fatal w/o liver transplant. Now you can eat a Costco bottle of APAP, but if you get NAC in 4 hrs it's universal survival. Try getting an RCT past an IRB for NAC.

      1 reply 0 retweets 5 likes
    4. Lee Loyd‏ @leeloyd1 24 Oct 2020
      Replying to @RNickGorton @gorskon and

      Even in the operating room, use of surgical masks is basically for ‘tradition’ and maintaining order. Mask use has been studied time and time again with similar results. But sure, all of a sudden they work..https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4480558/ …

      3 replies 0 retweets 1 like
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    6. Lee Loyd‏ @leeloyd1 24 Oct 2020
      Replying to @JonathanWHendry @RNickGorton and

      The literature I linked was a review of RCTs genius.... keep up

      1 reply 0 retweets 0 likes
    7. David Gorski, MD, PhD‏Verified account @gorskon 24 Oct 2020
      Replying to @leeloyd1 @JonathanWHendry and

      You’re very silly if you think this is a “gotcha.” I’m way ahead of you there, skippy. (Masks in the OR are also discussed.)https://sciencebasedmedicine.org/bouffant-caps-versus-skull-caps-in-the-operating-room-a-no-holds-barred-cage-match/ …

      1 reply 1 retweet 11 likes
    8. David Gorski, MD, PhD‏Verified account @gorskon 24 Oct 2020
      Replying to @gorskon @leeloyd1 and

      Now let’s see if our genius can tell us the difference between masks and wound contamination in the OR with bacteria and mask use and aerosol transmission of a contagious respiratory virus.🙄

      2 replies 0 retweets 12 likes
    9. Lee Loyd‏ @leeloyd1 24 Oct 2020
      Replying to @gorskon @JonathanWHendry and

      The literature review included viruses as well. Considering a viral particle is many times smaller than a bacteria, and the fact that n95 masks are the only useful measures for aerosols...except they protect the wearer...I can offer quite a bit to that convo

      1 reply 0 retweets 0 likes
    10. keithlaw‏Verified account @keithlaw 24 Oct 2020
      Replying to @leeloyd1 @gorskon and

      The droplet/aerosol claim is a false dichotomy, and because COVID-19 isn't traveling 'naked' in the air and is less contagious than virii like measles, droplet transmission is far more important than aerosol. https://www.acpjournals.org/doi/10.7326/M20-5008 …

      2 replies 1 retweet 11 likes
      David Gorski, MD, PhD‏Verified account @gorskon 24 Oct 2020
      Replying to @keithlaw @leeloyd1 and

      Yep. It’s a continuum. Yes, aerosol transmission can occur, but it’s much less important than larger respiratory droplets.

      2:02 PM - 24 Oct 2020
      • 2 Likes
      • Nick Gorton, MD 🏳️‍🌈🐾 keithlaw
      1 reply 0 retweets 2 likes

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